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Article
A small molecule compound targeting hemagglutinin inhibits influenza A virus and exhibits broad-spectrum antiviral activity
Influenza A virus (IAV) is a widespread pathogen that poses a significant threat to human health, causing pandemics with high mortality and pathogenicity. Given the emergence of increasingly drug-resistant str...
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Article
Thermoresponsive Fluorescent Semicrystalline Polymers Decorated with Aggregation Induced Emission Luminogens
Thermoresponsive fluorescent polymers (TFPs) with unique temperature-dependent luminescent properties are of great importance for the development of new functional devices in recent years. Herein, we facilely ...
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Article
Synthesis of isotactic polystyrene-block-polyethylene by the combination of sequential monomer addition and hydrogenation of 1,4-trans-polybutadiene block
Herein, we demonstrate the synthesis of a well-defined diblock copolymer consisting of isotactic polystyrene (iPS) and linear polyethylene, isotactic polystyrene-block-polyethylene (iPS-b-PE), by the combination ...
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Article
Fluorescent quantum yield of pyrene probe in ultrathin polymer films
The fluorescently labelled polymers including pyrene-labelled polystyrene (PyPS) and pyrene-labelled poly(methyl methacrylate) (PyPMMA) with narrow molecular weight distributions were synthesized by the atom t...
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Article
Glass transition and quantum yield for fluorescent labelled polystyrene core-forming block in self-assembled nanomicelles of amphiphilic diblock copolymers
Amphiphilic fluorescent diblock copolymers containing a pyrene-labelled polystyrene (PyPS) block, PyPS-block-poly(acrylic acid) (PyPS-b-PAA) and PyPS-block-poly(ethylene oxide) (PyPS-b-PEO) were synthesized by at...
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Article
Open AccessIsolation and full-length genome analysis of mosquito-borne Manzanilla virus from Yunnan Province, China
There have been four strains on Manzanilla virus (MANV) identified to date. Here, we identify a novel MANV strain (DHL10M107) isolated from Culex tritaeniorhynchus Giles mosquitoes from Ruili city, Dehong prefect...
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Article
Crystallization-driven self-assembly of isotactic polystyrene in N, N-dimethylformamide
Herein we demonstrate crystallization-driven self-assembly of isotactic polystyrene (iPS) with high isotacticity and narrow molecular weight distribution and crystallization-induced switching of the morphology of...
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Article
Open AccessHuman rabies surveillance and control in China, 2005–2012
Rabies reemerged in China during the 1990s with a gradual increase in the number and geographical dispersion of cases. As a consequence, a national surveillance program was introduced in 2005 to investigate th...
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Article
Crystalline-coil diblock copolymers of syndiotactic polypropylene-b- poly(ethylene oxide): synthesis, solution self-assembly, and confined crystallization in nanosized micelle cores
In this paper, two crystalline-coil diblock copolymers consisting of blocks of syndiotactic polypropylene (sPP) with different syndiotacticities ([rrrr]sPP1 = 0.78, [rrrr]sPP2 = 0.94) and poly(ethylene oxide) (PE...
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Article
Comparison of RFFIT tests with different standard sera and testing procedures
The World Health Organization (WHO) standard assay for determining antibody level is the rapid fluorescent focus inhibition test (RFFIT) and is used to determine the degree of immunity after vaccination agains...
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Article
The full-length genome analysis of a street rabies virus strain isolated in Yunnan province of China
The epidemic of rabies has rapidly increased and expanded in Yunnan province in recent years. In order to further analyze and understand the etiological reasons for the rapid expansion of rabies in Yunnan, a s...
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Article
Preparation and identification of anti-rabies virus monoclonal antibodies
To provide a foundation for the development of rapid and specific methods for the diagnosis of rabies virus infection, anti-rabies virus monoclonal antibodies were prepared and rabies virus nucleoprotein and h...
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Article
Molecular characterization of viral G gene in emerging and Re-emerging areas of rabies in China, 2007 to 2011
In recent years (2007 to 2011), although the overall number of rabies cases in China has decreased, there is evidence of emerging or re-emerging cases in regions without previous rabies cases or with low incid...
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Article
Simultaneous detection of three arboviruses using a triplex RT-PCR enzyme hybridization assay
Arboviruses represent a serious problem to public health and agriculture worldwide. Fast, accurate identification of the viral agents of arbovirus-associated disease is essential for epidemiological surveillan...
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Article
Analysis on factors related to rabies epidemic in China from 2007–2011
To analyze features of the rabies epidemic in China between 2007 and 2011, identify factors influencing the epidemic and to provide a scientific basis for further control and prevention of rabies, Descriptive ...
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Article
Open AccessEpidemiological investigations of human rabies in China
The epidemic of rabies showed a rising trend in China in recent years. To identify the potential factors involved in the emergence, we investigated and analyzed the status and characteristics of human rabies b...
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Article
Substitutions of 169Lys and 173Thr in nonstructural protein 1 influence the infectivity and pathogenicity of XJ-160 virus
An infectious clone (pBR-XJ160) was constructed using the full-length cDNA of the Sindbis-like XJ-160 virus. Two nucleotide mutations, causing amino acid changes at residue 169 from Lys to Arg and at residue 1...
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Article
Melting–Recrystallization of Block Copolymer Crystals in Confined Environments