3,536 Result(s)
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Article
Open AccessAnalyzing the correlation between low proportion of hobnail features in papillary thyroid carcinoma and clinical aggressiveness risk
Hobnail features may enhance the clinical aggressiveness of papillary thyroid carcinoma (PTC). However, whether a low proportion (<30%) of these features contributes to increased PTC aggressiveness remains unc...
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Article
Navβ2 Intracellular Fragments Contribute to Aβ1-42-Induced Cognitive Impairment and Synaptic Deficit Through Transcriptional Suppression of BDNF
A pathological hallmark of Alzheimer’s disease (AD) is the region-specific accumulation of the amyloid-beta protein (Aβ), which triggers aberrant neuronal excitability, synaptic impairment, and progressive cog...
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Article
Efficient elimination of trace iodide ions from medical wastewater by Cu/Cu2O@AC composites
Cu/Cu2O-modified activated carbon composites (Cu/Cu2O@AC) were synthesized via an one-step solvothermal method. The characterization results indicated that copper was uniformly dispersed on the surface of AC as n...
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Design parameter optimization method for a prestressed steel structure driven by multi-factor coupling
To achieve efficient structural design, it is crucial to reduce the cost of materials while ensuring structural safety. This study proposes an optimization method for design parameters (DPs) in a prestressed s...
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Article
Open AccessEasily misdiagnosed X-linked adrenoleukodystrophy
Addison’s disease and X-linked adrenoleukodystrophy (X-ALD) (Addison’s-only) are two diseases that need to be identified. Addison’s disease is easy to diagnose clinically when only skin and mucosal pigmentatio...
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Article
Boosting Stability and Efficiency: Defect-Rich Pd/NC Catalysts for Nitric Acid Reduction to Methyl Nitrite
Reduction of nitric acid reaction (2NO + HNO3 + 3CH3OH → 3CH3ONO + 2H2O) can convert by-product nitric acid into raw material methyl nitrite in the coal to ethylene glycol (CTEG) technology. This not only realize...
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Article
Crenobacter oryzisoli sp. nov., a novel phosphate-solubilizing bacterium isolated from the paddy soil
Two Gram-staining-negative, facultative anaerobic, rod-shaped and phosphate-solubilizing strains designated SG2303T and SG2305, were isolated from paddy soil in China. Phylogenetic analysis based on 16 S rRNA gen...
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Article
Observer-based Attitude Maneuver Control of Flexible Spacecraft: A Parametric Approach
To address the problem of control performance degradation caused by flexible attachment vibrations and external disturbances during attitude maneuvering of flexible spacecraft, this paper proposes a parametric...
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Article
Machine Learning: A Potential Therapeutic Tool to Facilitate Neonatal Therapeutic Decision Making
Bacterial infection is one of the major causes of neonatal morbidity and mortality worldwide. Finding rapid and reliable methods for early recognition and diagnosis of bacterial infections and early individual...
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Article
An autonomous positioning method for fire robots with multi-source sensors
The present technology, based on laser and visual SLAM navigation and positioning, does not apply to the event of a fire in a room where there is a large amount of smoke, for its increasingly obvious defects. ...
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Article
Open AccessTagging large CNV blocks in wheat boosts digitalization of germplasm resources by ultra-low-coverage sequencing
The massive structural variations and frequent introgression highly contribute to the genetic diversity of wheat, while the huge and complex genome of polyploid wheat hinders efficient genoty** of abundant v...
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Article
A robust strategy for realizing highly-efficient passive alignment of fiber ribbons to integrated polymer waveguides
The connection between ribbon fibers and optical waveguides is an ideal method for achieving precise coupling with other standard devices and is a key technology for the practical application of various integr...
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Article
1D Convolutional Seismic Event Classification Method Based on Attention Mechanism and Light Inception Block
Waveforms of artificially induced explosions and collapse events recorded by the seismic network share similarities with natural earthquakes. Failure to identify and screen them in a timely manner can introduc...
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Article
A machine learning-based calibration method for strength simulation of self-piercing riveted joints
This paper presents a new machine learning-based calibration framework for strength simulation models of self-piercing riveted (SPR) joints. Strength simulations were conducted through the integrated modeling ...
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Article
A non-invasive artificial intelligence model for identifying axillary pathological complete response to neoadjuvant chemotherapy in breast cancer: a secondary analysis to multicenter clinical trial
This study aims to develop a stacking model for accurately predicting axillary lymph node (ALN) response to neoadjuvant chemotherapy (NAC) using longitudinal MRI in breast cancer.
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Article
Structural and mechanistic basis for nucleosomal H2AK119 deubiquitination by single-subunit deubiquitinase USP16
Epigenetic regulators have a crucial effect on gene expression based on their manipulation of histone modifications. Histone H2AK119 monoubiquitination (H2AK119Ub), a well-established hallmark in transcription...
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Article
Effectiveness of Lianhua Qingwen Granule and **gyin Gubiao Prescription in Omicron BA.2 Infection and Hospitalization: A Real-World Study of 56,244 Cases in Shanghai, China
To examine the effectiveness of Chinese medicine (CM) Lianhua Qingwen Granule (LHQW) and **gyin Gubiao Prescription (JYGB) in asymptomatic or mild patients with Omicron infection in the shelter hospital.
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Article
Neuroprotective Effect and Mechanism of Tanreqing Injection on Ischemic Stroke: Insights from Network Pharmacology and in vivo Experiments
To explore the neuroprotective effects and mechanism of Tanreqing Injection (TRQ) on treating ischemic stroke based on network pharmacology and in vivo experimental validation.
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Article
Open AccessThe effect of hyperlipidemia on overall survival in patients with cancer was differentiated by BMI and hyperlipidemia type
The impact of lipids on the overall survival (OS) of patients with malignancy has not yet been clarified. This study aimed to evaluate the effect of hyperlipidemia on the OS among Chinese patients based on Bod...
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Open AccessCorrelation between hemoglobin and the risk of common malignant tumors: a 1999–2020 retrospective analysis and causal association analysis
The role of hemoglobin (HGB) in common malignant tumors remains unclear.