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Article
Open Access14-3-3 proteins regulate cullin 7-mediated Eag1 degradation
Mutations in the human gene encoding the neuron-specific Eag1 (KV10.1; KCNH1) potassium channel are linked to congenital neurodevelopmental diseases. Disease-causing mutant Eag1 channels manifest aberrant gating ...
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Article
Open AccessCullin 7 mediates proteasomal and lysosomal degradations of rat Eag1 potassium channels
Mammalian Eag1 (Kv10.1) potassium (K+) channels are widely expressed in the brain. Several mutations in the gene encoding human Eag1 K+ channel have been associated with congenital neurodevelopmental anomalies. C...
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Article
The Long-Term Effects of Mindfulness Added to Family Resilience-Oriented Couples Support Group on Psychological Well-Being and Cortisol Responses in Breast Cancer Survivors and Their Partners
The practice of mindfulness has not been well-developed for cancer survivors and their partners, and its effects on relational well-being and cortisol responses are unknown. This 14-month study aimed to examin...
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Article
Open AccessThe punctate localization of rat Eag1 K+channels is conferred by the proximal post-CNBHD region
In mammals, Eag K+ channels (KV10) are exclusively expressed in the brain and comprise two isoforms: Eag1 (KV10.1) and Eag2 (KV10.2). Despite their wide presence in various regions of the brain, the functional ro...
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Article
Densin-180 is Not a Transmembrane Protein
In the central nervous system, densin-180 (densin) is one of the major components of the post-synaptic density (PSD) of excitatory synapses. Through its intricate interaction with various post-synaptic protein...
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Article
Open AccessFunctional analysis of hepatitis B virus pre-s deletion variants associated with hepatocellular carcinoma
Naturally occurring pre-S deletion mutants have been identified in hepatitis B carriers and shown to be associated with the development of hepatocellular carcinoma. The phenotypes of these pre-S deletion genom...
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Article
Cytotoxic and apoptotic effects of prenylflavonoid artonin B in human acute lymphoblastic leukemia cells
To investigate the anticancer effects and molecular mechanism of artonin B on the human acute lymphoblastic leukemia CCRF-CEM cells compared with other prenylflavonoid compounds.
