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Article
Open AccessIdentification of circRNAs expression profiles and functional networks in parotid gland of type 2 diabetes mouse
Circular RNAs (circRNAs) are a novel kind of non-coding RNAs proved to play crucial roles in the development of multiple diabetic complications. However, their expression and function in diabetes mellitus (DM)...
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Article
Open AccessFactors influencing the accuracy of multimodal image fusion for oral and maxillofacial tumors: a retrospective study
Ensuring high accuracy in multimodal image fusion for oral and maxillofacial tumors is crucial before further application. The aim of this study was to explore the factors influencing the accuracy of multimoda...
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The Experience of Diagnosis and Management of Oral Maxillofacial Surgery, and Dental Education During the Pandemic
During the process of diagnosis and treatment of patients, medical staff in oral and maxillofacial surgery are prone to infection through respiratory droplets transmission and close contact with the infected p...
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Article
Natural develo** process of immunoglobulin G4-related sialadenitis after submandibular gland excision: a retrospective cohort study
This study aimed to evaluate the long-term outcome and quality of life of IgG4-related sialadenitis (IgG4-RS) patients after submandibular gland (SMG) excision without immunomediate therapy.
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Article
Open AccessA pair of long intergenic non-coding RNA LINC00887 variants act antagonistically to control Carbonic Anhydrase IX transcription upon hypoxia in tongue squamous carcinoma progression
Long noncoding RNAs (lncRNAs) are important regulators in tumor progression. However, their biological functions and underlying mechanisms in hypoxia adaptation remain largely unclear.
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Article
Diagnostic utility of submandibular and labial salivary gland biopsy in IgG4-related sialadenitis
The diagnostic utility of labial salivary gland (LSG) biopsy for IgG4-related sialadenitis remains undetermined. The purpose of the present study was to determine whether submandibular gland biopsy could be re...
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Article
Disruption of tight junction structure contributes to secretory dysfunction in IgG4-related sialadenitis
IgG4-related sialadenitis (IgG4-RS) is a chronic fibro-inflammatory disease characterized by swelling of salivary glands and varying degrees of xerostomia. Tight junctions (TJs) play an essential role in maint...
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Article
Ca2+-CaMKKβ pathway is required for adiponectin-induced secretion in rat submandibular gland
Adiponectin functions as a promoter of saliva secretion in rat submandibular gland via activation of adenosine monophosphate-activated protein kinase (AMPK) and increased paracellular permeability. Ca2+ mobilizat...
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Article
Open AccessTreatment of immunoglobulin G4-related sialadenitis: outcomes of glucocorticoid therapy combined with steroid-sparing agents
Immunoglobulin G4-related sialadenitis (IgG4-RS) is a newly recognized immune-mediated systemic disease. Despite its good response to steroid therapy, its treatment protocol is not standardized and the long-te...
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Article
Open AccessProteomic analysis reveals an impaired Ca2+/AQP5 pathway in the submandibular gland in hypertension
Hypertension is a systemic disorder that affects numerous physiological processes throughout the body. Improper sodium transport is a common comorbidity of hypertension, and sodium transport is also critical f...
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Article
Open AccessDevelopment and validation of the Chinese version of dry eye related quality of life scale
To develop the Chinese version of quality of life scale for dry eye patients based on the Impact of Dry Eye on Everyday Life (IDEEL) questionnaire and to assess the reliability and validity of the developed sc...
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Article
Decreased interaction between ZO-1 and occludin is involved in alteration of tight junctions in transplanted epiphora submandibular glands
Tight junctions (TJs) in salivary epithelium play an important role in regulating saliva secretion. Autologous transplantation of submandibular glands (SMGs) is an effective method to treat severe dry eye synd...
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Article
Muscarinic acetylcholine receptor-mediated tight junction opening is involved in epiphora in late phase of submandibular gland transplantation
Submandibular gland (SMG) autotransplantation is an effective therapy for treating severe dry eye syndrome. However, epiphora occurs in more than 40% of patients 6 months after operation. We previously found t...
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Article
Open AccessClinicopathological characteristics of immunoglobulin G4-related sialadenitis
Immunoglobulin G4-related disease (IgG4-RD) is a newly recognized fibro-inflammatory condition. Forty-two cases with immunoglobulin G4-related sialadenitis (IgG4-RS) confirmed by histopathological and immunohi...
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Open AccessMicrovascular autologous submandibular gland transplantation in severe cases of keratoconjunctivitis sicca
Dry eye syndrome is a relatively common disease of the tears and ocular surfaces that results in discomfort, visual disturbance, and tear film instability with possible damage to the ocular surfaces. Microvasc...
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Article
Open AccessBotulinum toxin A inhibits salivary secretion of rabbit submandibular gland
Botulinum toxin A (BTXA) has been used in several clinical trials to treat excessive glandular secretion; however, the precise mechanism of its action on the secretory function of salivary gland has not been f...
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Article
Antimetastatic effect of integrin IIb/IIIa inhibitors on salivary adenoid cystic carcinoma
Objectives: To investigate the relation between metastatic potential of salivary adenoid cystic carcinoma (SACC) and tumor cell-platelet adhesion, and the antimetastatic effect of integrin IIb/IIIa inhibitor o...
