-
Article
Open AccessMining the microbiota to identify gut commensals modulating neuroinflammation in a mouse model of multiple sclerosis
The gut microbiome plays an important role in autoimmunity including multiple sclerosis and its mouse model called experimental autoimmune encephalomyelitis (EAE). Prior studies have demonstrated that the mult...
-
Article
Open AccessAuthor Correction: Precise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes
-
Article
Open AccessPrecise quantification of bacterial strains after fecal microbiota transplantation delineates long-term engraftment and explains outcomes
Fecal microbiota transplantation (FMT) has been successfully applied to treat recurrent Clostridium difficile infection in humans, but a precise method to measure which bacterial strains stably engraft in recipie...
-
Article
Open AccessLimited intestinal inflammation despite diarrhea, fecal viral RNA and SARS-CoV-2-specific IgA in patients with acute COVID-19
Gastrointestinal symptoms are common in COVID-19 patients but the nature of the gut immune response to SARS-CoV-2 remains poorly characterized, partly due to the difficulty of obtaining biopsy specimens from i...
-
Article
Metabolic labeling puts the microbiome under the microscope
Seven years after the launch of the Human Microbiome Project, we still lack sufficient tools to visualize the microbiome in a living host. A new study provides experimental tools to label and track live anaero...
-
Article
Open AccessSequential transcriptional changes dictate safe and effective antigen-specific immunotherapy
Antigen-specific immunotherapy combats autoimmunity or allergy by reinstating immunological tolerance to target antigens without compromising immune function. Optimization of dosing strategy is critical for ef...
