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Article
Open AccessEpigenetic impacts of stress priming of the neuroinflammatory response to sarin surrogate in mice: a model of Gulf War illness
Gulf War illness (GWI) is an archetypal, medically unexplained, chronic condition characterised by persistent sickness behaviour and neuroimmune and neuroinflammatory components. An estimated 25–32% of the ove...
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Article
Open AccessIllness progression in chronic fatigue syndrome: a shifting immune baseline
Validation of biomarkers for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) across data sets has proven disappointing. As immune signature may be affected by many factors, our objective was to exp...
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Article
Open AccessA comparison of sex-specific immune signatures in Gulf War illness and chronic fatigue syndrome
Though potentially linked to the basic physiology of stress response we still have no clear understanding of Gulf War Illness (GWI), a debilitating condition presenting complex immune, endocrine and neurologic...
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Protocol
Psychoneuroimmunology and Natural Killer Cells: The Chromium Release Whole Blood Assay
Natural killer (NK) cells are an essential component of innate immunity. These lymphocytes are also sensitive barometers of the effects of endogenous and exogenous stressors on the immune system. This chapter ...
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Protocol
Exploring the Diagnostic Potential of Immune Biomarker Coexpression in Gulf War Illness
Complex disorders like Gulf War Illness (GWI) often defy diagnosis on the basis of a single biomarker and may only be distinguishable by considering the coexpression of multiple markers measured in response to...