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Article
Open AccessCTCF mutation at R567 causes developmental disorders via 3D genome rearrangement and abnormal neurodevelopment
The three-dimensional genome structure organized by CTCF is required for development. Clinically identified mutations in CTCF have been linked to adverse developmental outcomes. Nevertheless, the underlying mecha...
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Article
Open AccessApplication of the adaptive Monte Carlo method for uncertainty evaluation in the determination of total testosterone in human serum by triple isotope dilution mass spectrometry
The measurement uncertainty is a crucial quantitative parameter for assessing the reliability of the result. The study aimed to propose a new budget for uncertainty evaluation of a reference measurement proced...
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Article
Variant PRC1 subunit RYBP/YAF2 forms condensate with RING1B and promotes H2AK119ub deposition
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Article
Exosomal miR-129 and miR-342 derived from intermittent hypoxia-stimulated vascular smooth muscle cells inhibit the eIF2α/ATF4 axis from preventing calcified aortic valvular disease
This study aims to elucidate the role of miR-129/miR-342 loaded in exosomes derived from vascular smooth muscle cells (VSMCs) stimulated by intermittent hypoxia in calcified aortic valvular disease (CAVD). Bio...
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Article
Erratum to: Cenozoic giant coal-bearing basin belt discovered in China’s sea area
The original online version of this article was revised: (1) Article title was changed to “Cenozoic giant coal-bearing basin belt discovered in China’s sea and its adjacent areas”; (2) title of Fig. 2 “Coal se...
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Article
Open AccessFunctional dissection of PRC1 subunits RYBP and YAF2 during neural differentiation of embryonic stem cells
Polycomb repressive complex 1 (PRC1) comprises two different complexes: CBX-containing canonical PRC1 (cPRC1) and RYBP/YAF2-containing variant PRC1 (vPRC1). RYBP-vPRC1 or YAF2-vPRC1 catalyzes H2AK119ub through...
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Article
Preparation of a Novel Cationic Starch Bioflocculant and Its Application Performance in Municipal Sewage Odor Mitigation and Sludge Dewatering
The supernatant fluid and sludge produced by traditional polyacrylamide flocculant (PAM) flocculation of municipal sewage emit a strong odor, and the dewatering performance of flocculant flocculating sludge ba...
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Article
Mechanism of carbonate cementation and its influence on reservoir in **hu Formation of **hu Sag
Carbonate cements are the most abundant authigenic mineral and impact on physical properties greatly in sandstone reservoir. In this paper, **hu Formation of **hu Sag was taken as a target. Characteristics, ...
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Article
Cenozoic giant coal-bearing basin belt discovered in China’s sea area
Sea area is an important area of oil and gas exploration in China. It has been found that China’s sea area mainly consists of coal type oil and gas, and the exploration of coal-bearing series source rocks has ...
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Article
The gradual subduction-collision evolution model of Proto-South China Sea and its control on oil and gas
This study involved outcrop, drilling, seismic, gravity, and magnetic data to systematically document the geological records of the subduction process of Proto-South China Sea (PSCS) and establish its evolutio...
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Article
Differences of Polygonal Faults with Irregularly Polygonal Geometries: A Case Study from the Changchang Sag of Qiongdongnan Basin, Northern South China Sea
Polygonal faults (PFs) generally have a classic polygonal geometry in map view. However, under the influence of tectonic faults, diapirs, channels, and slopes, the classic polygonal geometry of PFs is not pres...
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Chapter
Development and Application Status of National Reference Materials for in Vitro Diagnostic Reagents
In vitro diagnosis refers to the activity of analyzing and testing samples (blood, body fluids, tissues, etc.) taken from a human body by means of chemical, physical, or biological analysis, so as to evaluate ...
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Chapter
Research and Development, Production, and Application Status of Quality Controls for in Vitro Diagnostic Reagents
As per requirements of ISO15189 Medical Laboratories-Requirements for Quality and Competence (2012), clinical laboratories providing medical laboratory services should meet the basic requirements of quality manag...
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Chapter and Conference Paper
Time Series Prediction of 5G Network Data Based on Improved EEMD-BiLSTM Prediction Model
5G networks are designed to support various emerging applications, such as the Internet of Things (IoT), autonomous vehicles, and smart cities, which require low latency, high throughput, and reliable connecti...
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Article
Differences of polygonal faults related to upper Miocene channels: a case study from the Beijiao sag of Qiongdongnan basin, South China Sea
Deep-water coarse-grained channels are embedded within a polygonal fault tier, and the polygonal faults (PFs) present non-polygonal geometries rather than classic polygonal geometry in plan view. However, PFs ...
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Article
Toughening Modification of Polylactic Acid by Long-Chain Hyperbranched Polymers Containing Polycaprolactone end Groups
The hyperbranched polyester (HBPEs) were synthesized by the "one-step method" and grafted with caprolactone (ε-Cl) to obtain long-chain hyperbranched polymers (LCHBPs-Cl). In this study, LCHBPs-Cl with Cl long...
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Article
3D velocity field reconstruction of gas-liquid two-phase flow based on space-time multi-scale binocular-PIV technology
for particle image velocimetry (PIV) technique, the two-dimensional (2D) PIV by one camera can only obtain 2D velocity field, while three-dimensional (3D) PIV based on tomography by three or four cameras is al...
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Article
Open AccessCTCF acetylation at lysine 20 is required for the early cardiac mesoderm differentiation of embryonic stem cells
The CCCTC-binding factor (CTCF) protein and its modified forms regulate gene expression and genome organization. However, information on CTCF acetylation and its biological function is still lacking. Here, we ...
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Article
Open AccessConstruction of an individualized clinical prognostic index based on ubiquitination-associated lncRNA in clear cell renal cell carcinoma patients
ccRCC is considered as the main subtype of RCC, which accounted for sixth deadliest cancer worldwide. Recently, ubiquitination has been reported to be closely involved in the progression of tumore. The purpose...
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Article
Size Control of In Situ Synthesized TiB2 Particles in Molten Aluminum
Aluminum-matrix nanocomposites offer advantageous properties over conventional aluminum alloys. However, controlling the size and size distribution of ceramic nanoparticles during in situ synthesis at high temper...
