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Article
Transient hyperglycemia in acute childhood illnesses: To attend or ignore?
Transient hyperglycemia occurs as a part of stress response in acute illnesses and is brought about by elevated levels of counter regulatory hormones. It is frequently encountered but the exact prevalence and ...
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Article
Persistent Pulmonary Hypertension of the Newborn
Persistent pulmonary hypertension of the newborn (PPHN) is characterized by severe hypoxemia shortly after birth, absence of cyanotic congenital heart disease, marked pulmonary hypertension, and vasoreactivity...
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Article
Circulating β Chemokine and MMP 9 as Markers of Oxidative Injury in Extremely Low Birth Weight Infants
Matrix metalloproteinases (MMPs) and chemokines seem to be induced by hyperoxia in preclinical studies. We hypothesized that O2 exposure immediately after birth is associated with altered blood spot MMP 9 and β c...
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Article
Hypoplastic Left Heart Syndrome, Restrictive Patent Foramen Ovale, and Pulmonary Valve Stenosis: An Unusual Combination
An infant presented with a rare combination of hypoplastic left heart syndrome, restricted patent foramen ovale, and moderately dysplastic pulmonary valve. In preparation for heart transplantation, bilateral p...
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Article
Isolated ruptured appendicitis presenting as pneumatosis intestinalis in a premature neonate
We report a novel case of ruptured appendicitis in a premature neonate which radiographically mimicked necrotizing enterocolitis with free intraperitoneal air. On exploratory laparotomy, both the large and sma...
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Article
Effect of inborn vs. outborn delivery on neurodevelopmental outcomes in infants with hypoxic–ischemic encephalopathy: secondary analyses of the NICHD whole-body cooling trial
The effect of birth location on hypothermia-related outcomes has not been rigorously examined in the literature. In this study, we determined whether birth location had an impact on the benefits of whole-body ...
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Article
Association Between Blood Spot Transforming Growth Factor-β and Patent Ductus Arteriosus in Extremely Low-Birth Weight Infants
Permanent ductal closure involves anatomic remodeling, in which transforming growth factor (TGF)-β appears to play a role. Our objective was to evaluate the relationship, if any, between blood spot TGF-β on da...
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Article
Association Between Anemia and Packed Cell Transfusion and Outcomes of Ventricular Septal Defect and Atrioventricular Canal Repair in Children
Data on the prevalence and impact of anemia and packed red blood cell (PRBC) transfusions in children with congenital heart disease are limited. Our objectives were to determine the prevalence of anemia and it...
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Article
When and How to Extubate Premature Infants from Mechanical Ventilation
Prolonged mechanical ventilation (MV) is associated with both short-term morbidities and neurodevelopmental impairment. The ability of clinicians to accurately predict successful extubation is limited. Extuba...
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Article
Association among prematurity (<30 weeks’ gestational age), blood pressure, urinary albumin, calcium, and phosphate in early childhood
There is a paucity of data on blood pressures (BP), urinary albumin, and mineral excretion in early childhood in contemporary cohorts of extremely low gestational age (GA) neonates. Our aim was to compare BPs ...
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Article
Late preterm birth and growth failure in childhood: What do we do now?
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Article
Association between sedation–analgesia and neurodevelopment outcomes in neonatal hypoxic-ischemic encephalopathy
To evaluate the association between sedation–analgesia (SA) during initial 72 h and death/disability at 18 months of age in neonatal hypoxic-ischemic encephalopathy (HIE).
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Article
Open AccessPractice variation in anti-epileptic drug use for neonatal hypoxic-ischemic encephalopathy among regional NICUs
While intercenter variation (ICV) in anti-epileptic drug (AED) use in neonates with seizures has been previously reported, variation in AED practices across regional NICUs has not been specifically and systema...
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Article
Feeding during transfusion and the risk of necrotizing enterocolitis in preterm infants
To evaluate the effect of withholding feeds during transfusion on transfusion associated acute gut injury (TRAGI).
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Article
In-hospital outcomes of neonates with hypoxic-ischemic encephalopathy receiving extracorporeal membrane oxygenation
To determine in-hospital outcomes of neonates with hypoxic ischemic encephalopathy (HIE) requiring extracorporeal membrane oxygenation (ECMO).
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Article
Response to Dr. Nair
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Article
A predictive model for extubation readiness in extremely preterm infants
To develop an estimator for predicting successful extubation for an individual preterm infant.
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Article
Echocardiographic prediction of severe pulmonary hypertension in neonates undergoing therapeutic hypothermia for hypoxic-ischemic encephalopathy
Among neonates undergoing whole body cooling for hypoxic-ischemic encephalopathy (HIE), to compare ventricular function in the presence and absence of pulmonary hypertension (PPHN) needing inhaled nitric oxide...
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Article
Utility of echocardiography in predicting mortality in infants with severe bronchopulmonary dysplasia
To determine the relationship between interventricular septal position (SP) and right ventricular systolic pressure (RVSP) and mortality in infants with severe BPD (sBPD).
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Article
Antimicrobial therapy utilization in neonates with hypoxic-ischemic encephalopathy (HIE): a report from the Children’s Hospital Neonatal Database (CHND)
Quantify antimicrobial therapy (AMT) use in newborns with hypoxic-ischemic encephalopathy treated with therapeutic hypothermia (HIE/TH).
