7 Result(s)

Article

Correction to: Is there a role for microbiome‑based approach in common variable immunodeficiency?

Remo Poto, Gianluca Ianiro, Amato de Paulis… in Clinical and Experimental Medicine (2023)

Article

Is there a role for microbiome-based approach in common variable immunodeficiency?

Common variable immunodeficiency (CVID) is a primary immunodeficiency characterized by low levels of serum immunoglobulins and increased susceptibility to infections, autoimmune disorders and cancer. CVID embr...

Remo Poto, Gianluca laniro, Amato de Paulis… in Clinical and Experimental Medicine (2023)

Article

Autoantibodies to IgE can induce the release of proinflammatory and vasoactive mediators from human cardiac mast cells

Mast cells are multifunctional immune cells with complex roles in tissue homeostasis and disease. Cardiac mast cells (HCMCs) are strategically located within the human myocardium, in atherosclerotic plaques, i...

Remo Poto, Vincenzo Patella, Gjada Criscuolo… in Clinical and Experimental Medicine (2023)

Article

Gender dimorphism in IgA subclasses in T2-high asthma

Immunoglobulin A (Chan in J Allergy Clin Immunol 134:1394–14014e4, 2014), the second most abundant immunoglobulin in serum, plays an important role in mucosal homeostasis. In human serum, there are two subclas...

Gilda Varricchi, Remo Poto, Bianca Covelli… in Clinical and Experimental Medicine (2023)

Article

Neutrophil extracellular traps and neutrophil-derived mediators as possible biomarkers in bronchial asthma

Neutrophils (PMNs) contain and release a powerful arsenal of mediators, including several granular enzymes, reactive oxygen species (ROS) and neutrophil extracellular traps (NETs). Although airway neutrophilia...

Gilda Varricchi, Luca Modestino, Remo Poto… in Clinical and Experimental Medicine (2022)

Article

Vascular endothelial growth factors and angiopoietins as new players in mastocytosis

Mastocytosis is a disorder characterized by the abnormal proliferation and/or accumulation of mast cells in different organs. More than 90% of patients with systemic mastocytosis have a gain-of-function mutati...

Simone Marcella, Angelica Petraroli… in Clinical and Experimental Medicine (2021)

Article

Roles of Immune Cells in Hereditary Angioedema

Hereditary angioedema (HAE) is a rare genetic disease, characterized by recurrent and unexpected potentially life-threatening mucosal swelling. HAE may be further classified into HAE with C1‐inhibitor deficien...

Anne Lise Ferrara, Leonardo Cristinziano… in Clinical Reviews in Allergy & Immunology (2021)