7 Result(s)

Article

Clinical features and potential markers of disease in idiopathic non-histaminergic angioedema, a real-life study

Idiopathic non-histaminergic acquired angioedema (InH-AAE) is a rare disease, with unknown etiology and pathogenesis, characterized by recurrent clinical manifestations and resistance to antihistamines and cor...

Ilaria Mormile, Maria Celeste Gigliotti, Anne Lise Ferrara… in Immunologic Research (2024)

Article

Melanoma-derived soluble mediators modulate neutrophil biological properties and the release of neutrophil extracellular traps

Polymorphonuclear neutrophils (PMNs) are the main effector cells in the inflammatory response. The significance of PMN infiltration in the tumor microenvironment remains unclear. Metastatic melanoma is the mos...

Luca Modestino, Leonardo Cristinziano… in Cancer Immunology, Immunotherapy (2023)

Article

Interplay between C1-inhibitor and group IIA secreted phospholipase A₂ impairs their respective function

High levels of human group IIA secreted phospholipase A₂ (hGIIA) have been associated with various inflammatory disease conditions. We have recently shown that hGIIA activity and concentration are increased in th...

Anne Lise Ferrara, Maria Bova, Angelica Petraroli, Daniela Marasco… in Immunologic Research (2023)

Article

Vascular endothelial growth factors and angiopoietins as new players in mastocytosis

Mastocytosis is a disorder characterized by the abnormal proliferation and/or accumulation of mast cells in different organs. More than 90% of patients with systemic mastocytosis have a gain-of-function mutati...

Simone Marcella, Angelica Petraroli… in Clinical and Experimental Medicine (2021)

Article

Pathways of Neutrophil Granulocyte Activation in Hereditary Angioedema with C1 Inhibitor Deficiency

Hereditary angioedema (HAE) with C1-inhibitor deficiency belongs to bradykinin-mediated angioedemas. It is characterized by recurrent subcutaneous and/or submucosal swelling episodes (HAE attacks) and erythema...

Erika Kajdácsi, Nóra Veszeli, Blanka Mező… in Clinical Reviews in Allergy & Immunology (2021)

Article

Roles of Immune Cells in Hereditary Angioedema

Hereditary angioedema (HAE) is a rare genetic disease, characterized by recurrent and unexpected potentially life-threatening mucosal swelling. HAE may be further classified into HAE with C1‐inhibitor deficien...

Anne Lise Ferrara, Leonardo Cristinziano… in Clinical Reviews in Allergy & Immunology (2021)

Article

Abstracts from the 10th C1-inhibitor deficiency workshop

Alvin H. Schmaier, Marco Cicardi, Avner Reshef… in Allergy, Asthma & Clinical Immunology (2017)