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Open AccessImmortalized murine tenocyte cells: a novel and innovative tool for tendon research
Primary tenocytes rapidly undergo senescence and a phenotypic drift upon in vitro monolayer culture, which limits tendon research. The Ink4a/Arf locus encodes the proteins p16Ink4a/Arf and p14ARF (p19ARF in mice)...
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Open AccessSpecies variations in tenocytes’ response to inflammation require careful selection of animal models for tendon research
For research on tendon injury, many different animal models are utilized; however, the extent to which these species simulate the clinical condition and disease pathophysiology has not yet been critically eval...
