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    Article

    A bipartite structural organization defines the SERINC family of HIV-1 restriction factors

    The human integral membrane protein SERINC5 potently restricts HIV-1 infectivity and sensitizes the virus to antibody-mediated neutralization. Here, using cryo-EM, we determine the structures of human SERINC5 ...

    Valerie E. Pye, Annachiara Rosa, Cinzia Bertelli… in Nature Structural & Molecular Biology (2020)

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    Protocol

    Potential Zoonotic Infection of Porcine Endogenous Retrovirus in Xenotransplantation

    Porcine endogenous retrovirus (PERV) is considered the major biosafety issue in xenotransplantation. Several techniques have been employed for the analysis of the PERV status in the animal donor and for the as...

    Giada Mattiuzzo, Yasuhiro Takeuchi, Linda Scobie in Xenotransplantation (2012)