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    A bipartite structural organization defines the SERINC family of HIV-1 restriction factors

    The human integral membrane protein SERINC5 potently restricts HIV-1 infectivity and sensitizes the virus to antibody-mediated neutralization. Here, using cryo-EM, we determine the structures of human SERINC5 ...

    Valerie E. Pye, Annachiara Rosa, Cinzia Bertelli… in Nature Structural & Molecular Biology (2020)