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  1. Article

    Open Access

    Vitamin D and Wnt3A have additive and partially overlap** modulatory effects on gene expression and phenotype in human colon fibroblasts

    The Wnt/β-catenin signalling pathway is essential for intestinal epithelium homeostasis, but its aberrant activation is a hallmark of colorectal cancer (CRC). Several studies indicate that the bioactive vitami...

    Gemma Ferrer-Mayorga, Núria Niell, Ramón Cantero… in Scientific Reports (2019)

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  2. No Access

    Chapter

    Wnt Pathway at a Glance: From the Deep of the Crypts to the Current Ways of Targeting

    Wnt/β-catenin signalling pathway is crucial for the formation of many tissues and organs during development. In recent years, this pathway has also been found to regulate the biology of stem cells in the intes...

    Antonio Barbáchano, María Jesús Larriba… in Stem Cells in Cancer: Should We Believe or… (2014)