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Open AccessVitamin D and Wnt3A have additive and partially overlap** modulatory effects on gene expression and phenotype in human colon fibroblasts
The Wnt/β-catenin signalling pathway is essential for intestinal epithelium homeostasis, but its aberrant activation is a hallmark of colorectal cancer (CRC). Several studies indicate that the bioactive vitami...
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Wnt Pathway at a Glance: From the Deep of the Crypts to the Current Ways of Targeting
Wnt/β-catenin signalling pathway is crucial for the formation of many tissues and organs during development. In recent years, this pathway has also been found to regulate the biology of stem cells in the intes...