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  1. Article

    Open Access

    Skeletal muscle transcriptome in healthy aging

    Age-associated changes in gene expression in skeletal muscle of healthy individuals reflect accumulation of damage and compensatory adaptations to preserve tissue integrity. To characterize these changes, RNA ...

    Robert A. Tumasian III, Abhinav Harish, Gautam Kundu, Jen-Hao Yang… in Nature Communications (2021)

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  2. No Access

    Article

    Tumor-derived osteopontin drives the resident fibroblast to myofibroblast differentiation through Twist1 to promote breast cancer progression

    Tumor-stroma interactions are important determinants for the disease course in cancer. While stromal influence has been known to often play a tumor-promoting role, incomplete mechanistic insight into this phen...

    Ramesh Butti, Ramakrishna Nimma, Gautam Kundu, Anuradha Bulbule… in Oncogene (2021)

  3. No Access

    Article

    Survey of the Arc Epigenetic Landscape in Normal Cognitive Aging

    Aging is accompanied by aberrant gene expression that ultimately affects brain plasticity and the capacity to form long-term memories. Immediate-early genes (IEGs) play an active role in these processes. Using...

    Craig Myrum, Joshua Kittleson, Supriyo De, Bonnie R. Fletcher… in Molecular Neurobiology (2020)

  4. Article

    Open Access

    Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma

    Melanoma is a form of cancer that initiates in melanocytes. Melanoma has multiple phenotypically distinct subpopulation of cells, some of them have embryonic like plasticity which are involved in self-renewal,...

    Dhiraj Kumar, Mahadeo Gorain, Gautam Kundu, Gopal C. Kundu in Molecular Cancer (2017)

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