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Article
Prognostic value of dynamic changes of pre- and post-operative tumor markers in colorectal cancer
Colorectal cancer (CRC) prognosis assessment is vital for personalized treatment plans. This study investigates the prognostic value of dynamic changes of tumor markers CEA, CA19-9, CA125, and AFP before and a...
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Article
Open AccessPrognostic value of normal levels of preoperative tumor markers in colorectal cancer
Carcinoembryonic antigen (CEA), carbohydrate antigen 19-9 (CA19-9), carbohydrate antigen 125 (CA125), and alpha-fetoprotein (AFP) are widely used tumor markers for colorectal cancer (CRC), but their clinical s...
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Article
Open AccessSingle-cell analysis unveils activation of mast cells in colorectal cancer microenvironment
The role of mast cells (MCs) in colorectal cancer (CRC) remains unclear, and a comprehensive single-cell study on CRC MCs has not been conducted. This study used a multi-omics approach, integrating single-cell...
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Article
A nomogram was developed using clinicopathological features to predict postoperative liver metastasis in patients with colorectal cancer
The objective of this study is to examine the risk factors that contribute to the development of liver metastasis (LM) in patients who have suffered radical resection for colorectal cancer (CRC), and to establ...
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Article
Open AccessNecessity of prophylactic splenic hilum lymph node clearance for middle and upper third gastric cancer: a network meta-analysis
It remains controversial whether prophylactic No.10 lymph node clearance is necessary for gastric cancer. Thus, the present study aims to investigate the impact of prophylactic No.10 lymph node clearance on th...
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Article
Open AccessLow lymphocyte count and high monocyte count predicts poor prognosis of gastric cancer
Existing data about the prognostic value of absolute count of blood cells in gastric cancer was limited. Thus, the present study aims to investigate the prognostic value of absolute count of white blood cell (...
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Article
Open AccessPrognostic value of differentiation status in gastric cancer
Up to date, investigation of the prognostic value of differentiation status mainly focused on signet ring cell and mucinous gastric cancer. Thus, the present study aims to investigate the clinicopathological f...
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Article
Open AccessClinicopathological features, surgical strategy and prognosis of duodenal gastrointestinal stromal tumors: a series of 300 patients
The relatively low incidence of duodenal gastrointestinal stromal tumors (GISTs) and the unique anatomy make the surgical management and outcomes of this kind of tumor still under debate. Thus, this study aime...
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Article
Open AccessImpact of body mass index on surgical outcomes of gastric cancer
The association between body mass index (BMI) and clinical outcomes of gastric cancer were still under debate. The aim of the present study was to investigate the impact of BMI on intraoperative conditions, po...
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Article
Open AccessMeta-analysis comparing laparoscopic versus open resection for gastric gastrointestinal stromal tumors larger than 5 cm
Data on the safety and feasibility of laparoscopic versus open resection for gastric gastrointestinal stromal tumors (GISTs) larger than 5 cm are limited. Therefore, the aim of this meta-analysis was to compar...
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Article
Open AccessDiagnostic and prognostic value of CEA, CA19–9, AFP and CA125 for early gastric cancer
The diagnostic and prognostic significance of carcinoembryonic antigen (CEA), carbohydrate associated antigen 19–9 (CA19–9), alpha-fetoprotein (AFP) and cancer antigen 125 (CA125) in early gastric cancer have ...
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Article
Open AccessClinicopathological features and prognosis of gastric adenosquamous carcinoma
Data about primary gastric adenosquamous carcinoma (ASC) was limited due to rare incidence. Thus, the present study aims to investigate clinicopathological features and prognosis of gastric ASC. Cases of gastr...
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Article
Open AccessPrognosis and Progression of ESCC Patients with Perineural Invasion
Perineural invasion (PNI) has been recognized as a poor prognostic factor in several malignancies, but the definition and pathogenesis of PNI in esophageal squamous cell carcinoma (ESCC) remains to be defined....
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Article
Open AccessThe length of proximal margin does not influence the prognosis of Siewert type II/III adenocarcinoma of esophagogastric junction after transhiatal curative gastrectomy
The optimal length of proximal margin for Siewert type II/III adenocarcinoma of the esophagogastric junction (AEJ) is still need to be clarified. The aim of the present study was to investigate the appropriate...
