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Open AccessDEVD-Based Hydrogelator Minimizes Cellular Apoptosis Induction
Herein, we report the rational design of a DEVD-based heptapeptide hydrogelator 1 which is susceptible to caspase-3 (CASP3) and its isomeric control hydrogelator 2 with a DEDV-based heptapeptide sequence. Self...
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Article
Open AccessControlled intracellular self-assembly of gadolinium nanoparticles as smart molecular MR contrast agents
Herein we developed a new “smart” Gd-based MR contrast agent (i.e., 1) which is susceptive to furin, a protease overexpressed in tumor. Under the action of furin, 1 condenses to form dimers (1-Ds) and the latt...