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Open AccessMitochondrial SIRT3 as a protective factor against cyclosporine A-induced nephrotoxicity
Sirtuin3 (SIRT3), a mitochondrial deacetylase, has been shown to be involved in various kidney diseases. In this study, we aimed to clarify the role of SIRT3 in cyclosporine-induced nephrotoxicity and the asso...
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Open AccessAuthor Correction: Importance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study
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Open AccessImportance of dialysis specialists in early mortality in elderly hemodialysis patients: a multicenter retrospective cohort study
The early mortality rate in elderly patients undergoing hemodialysis is more than twice that in young patients, requiring more specialized healthcare. We investigated whether the number of professional dialysi...
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Article
Open AccessEffect of low-density lipoprotein level and mortality in older incident statin-naïve hemodialysis patients
This study aimed to analyze low-density lipoprotein cholesterol (LDL-C) levels and their relationship with mortality in order to identify the appropriate lipid profile for older Korean hemodialysis patients.
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Open AccessAssociation between physical activity and risk of renal function decline and mortality in community-dwelling older adults: a nationwide population-based cohort study
Physical activity (PA) is an important risk factor associated with health outcomes. However, the relationship between PA and kidney function decline in older adults remains unclear. We examined the influence o...
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Open AccessWaist–hip ratio measured by bioelectrical impedance analysis as a valuable predictor of chronic kidney disease development
Obesity is a major health problem worldwide and is associated with chronic kidney disease (CKD). Body mass index (BMI) is a common method of diagnosing obesity, but there are concerns about its accuracy and ab...
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Open AccessImpact of acute kidney injury on long-term adverse outcomes in obstructive uropathy
Obstructive uropathy is known to be associated with acute kidney injury (AKI). This study aimed to investigate the etiologies, clinical characteristics, consequences and also assess the impact of AKI on long-t...
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Open AccessThe beneficial effects of menopausal hormone therapy on renal survival in postmenopausal Korean women from a nationwide health survey
Several studies have demonstrated the nephroprotective effects of estrogen on renal damage. In light of the inconsistent results of previous findings, this study aims to evaluate the in-depth role of menopausa...
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Open AccessImpact of water consumption on renal function in the general population: a cross-sectional analysis of KNHANES data (2008–2017)
The renoprotective effect of water intake remains unclear. We aimed to investigate the relationship between water intake and renal impairment in the Korean general population, focusing on individual difference...
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Dipstick proteinuria and cancer incidence: a nationwide population-based study
The association between proteinuria and malignancy has been frequently reported, but the issue is matter of controversy. Thus, in order to shed light on the association, we evaluated proteinuria as a risk fact...
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Open AccessGait speed and handgrip strength as predictors of all-cause mortality and cardiovascular events in hemodialysis patients
Low physical performance in patients undergoing maintenance hemodialysis is associated with a high mortality rate. We investigated the clinical relevance of gait speed and handgrip strength, the two most commo...
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Open AccessHigh dose haemodialysis and haemodiafiltration parameters and the relationship with advanced vascular calcification
Vascular calcification (VC) is a risk factor for cardiovascular disease in end-stage renal disease (ESRD) patients undergoing maintenance haemodialysis (MHD). However, evidence is still insufficient about the ...
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Open AccessThe Effect of Strict Volume Control Assessed by Repeated Bioimpedance Spectroscopy on Cardiac Function in Peritoneal Dialysis Patients
Adequate fluid management plays an important role in decreasing cardiovascular risk in peritoneal dialysis (PD) patients. We evaluated whether strict volume control monitored by bioimpedance spectroscopy (BIS)...
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Open AccessThe role of nuclear factor erythroid-2-related factor 2 expression in radiocontrast-induced nephropathy
Radiocontrast-induced nephropathy (CIN) is the third most common cause of acute renal failure. The pathophysiology of CIN is related to tubular injury caused by oxidative stress, and nuclear factor erythroid-2...
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Raoultella planticola peritonitis in a patient on continuous ambulatory peritoneal dialysis
A 65-year-old man on continuous ambulatory peritoneal dialysis was admitted with peritonitis. Empirical antibiotic therapy was initiated, and Raoultella planticola was identified in the peritoneal fluid culture. ...
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Immunologic research in kidney ischemia/reperfusion injury at Johns Hopkins University
Kidney ischemia/reperfusion injury (IRI) is a common and serious problem in hospitalized patients. Immune cell trafficking and leukocyte-endothelial adhesion potentiate kidney IRI. An important immunomodulator...
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The interaction between ischemia–reperfusion and immune responses in the kidney
Kidney ischemia–reperfusion injury (IRI) engages both the innate and adaptive immune responses. Cellular mediators of immunity, such as dendritic cells, neutrophils, macrophages, natural killer T, T, and B cel...