17 Result(s)
within
Gang** Han
Science, Humanities and Social Sciences, multidisciplinary
-
Article
Open AccessBacteriophage EPP-1, a potential antibiotic alternative for controlling edwardsiellosis caused by Edwardsiella piscicida while mitigating drug-resistant gene dissemination
Edwardsiella piscicida causes significant economic losses to the aquaculture industry worldwide. Phage-based biocontrol methods are experiencing a renaissance because of the spread of drug-resistant genes and bac...
-
Article
Open AccessX-ray-activated polymerization expanding the frontiers of deep-tissue hydrogel formation
Photo-crosslinking polymerization stands as a fundamental pillar in the domains of chemistry, biology, and medicine. Yet, prevailing strategies heavily rely on ultraviolet/visible (UV/Vis) light to elicit in s...
-
Article
Open AccessAlternations in the human skin, gut and vaginal microbiomes in perimenopausal or postmenopausal Vulvar lichen sclerosus
Vulvar lichen sclerosus (VLS) is a chronic and progressive dermatologic condition that can cause physical dysfunction, disfigurement, and impaired quality of life. However, the etiology of VLS remains unknown....
-
Article
Open AccessResearch on the variation law of floor stress information entropy in upper protective layer mining based on Brillouin optical fiber sensing
The characteristics of floor failure and stress changes during the mining process of protective layers are crucial for determining the effectiveness of pressure relief. Three boreholes were designed in the 211...
-
Article
Open AccessAn extraordinary fossil captures the struggle for existence during the Mesozoic
Dinosaurs and mammals have coexisted for the last ~ 230 million years. Both groups arose during the Late Triassic and diversified throughout the Mesozoic and into the Cenozoic (the latter in the form of birds)...
-
Article
Open AccessThe Cas9-gRNA ribonucleoprotein complex-mediated editing of pyrG in Ganoderma lucidum and unexpected insertion of contaminated DNA fragments
Gene editing is a promising alternative to traditional breeding for the generation of new mushroom strains. However, the current approach frequently uses Cas9-plasmid DNA to facilitate mushroom gene editing, w...
-
Article
Open AccessRed light-driven electron sacrificial agents-free photoreduction of inert aryl halides via triplet-triplet annihilation
Selective photoactivation of inert aryl halides is a fundamental challenge in organic synthesis. Specially, the long-wavelength red light is more desirable than the widely-applied blue light as the excitation ...
-
Article
Open AccessEnzymatic enhancing of triplet–triplet annihilation upconversion by breaking oxygen quenching for background-free biological sensing
Triplet-triplet annihilation upconversion nanoparticles have attracted considerable interest due to their promises in organic chemistry, solar energy harvesting and several biological applications. However, tr...
-
Article
Open AccessLong wavelength single photon like driven photolysis via triplet triplet annihilation
Photolysis has enabled the occurrence of numerous discoveries in chemistry, drug discovery and biology. However, there is a dearth of efficient long wavelength light mediated photolysis. Here, we report genera...
-
Article
Open AccessPathway and kinetics of malachite green biodegradation by Pseudomonas veronii
Malachite green is a common environmental pollutant that poses a great threat to non-target organisms, including humans. This study reports the characterization of a bacterial strain, Pseudomonas veronii JW3-6, w...
-
Article
Open AccessIncreased glucocorticoid receptor activity and proliferation in metastatic colon cancer
Metastasis is regarded as the fatal hallmark for colon cancer, but molecular mechanisms responsible for it have remained poorly defined. Glucocorticoid receptor (GR) within the tumor microenvironment mediates ...
-
Article
A Jurassic gliding euharamiyidan mammal with an ear of five auditory bones
Gliding is a distinctive locomotion type that has been identified in only three mammal species from the Mesozoic era. Here we describe another Jurassic glider that belongs to the euharamiyidan mammals and show...
-
Article
Open AccessAltered Adipose-Derived Stem Cell Characteristics in Macrodactyly
Macrodactyly is a congenital disease characterized by aggressive overgrowth of adipose tissue in digits or limbs frequently accompanied with hyperostosis and nerve enlargement; its pathological mechanism is po...
-
Article
Stable colloids in molten inorganic salts
A class of colloids is reported in which inorganic solute particles—such as metals and semiconductors—are dispersed in molten inorganic salts.
-
Article
Open AccessA Salmonella nanoparticle mimic overcomes multidrug resistance in tumours
Salmonella enterica serotype Typhimurium is a food-borne pathogen that also selectively grows in tumours and functionally decreases P-glycoprotein (P-gp), a multidrug resistance transporter. Here we report that t...
-
Article
Open AccessHexose enhances oligonucleotide delivery and exon skip** in dystrophin-deficient mdx mice
Carbohydrate-based infusion solutions are widely used in the clinic. Here we show that co-administration of phosphorodiamidate morpholino oligomers (PMOs) with glucose enhances exon-skip** activity in Duchen...
-
Article
A new raptorial dinosaur with exceptionally long feathering provides insights into dromaeosaurid flight performance
Microraptorines are a group of predatory dromaeosaurid theropod dinosaurs with aerodynamic capacity. These close relatives of birds are essential for testing hypotheses explaining the origin and early evolutio...
