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Virtual Learning Collaborative Compared to Technical Assistance as a Strategy for Implementing Health Promotion in Routine Mental Health Settings: A Hybrid Type 3 Cluster Randomized Trial
Despite widespread use of learning collaboratives, few randomized trials have evaluated their effectiveness as a strategy for implementing evidence based practices. This randomized trial evaluated the effectiv...
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Article
Open AccessSilencing of Testin expression is a frequent event in spontaneous lymphomas from Trp53-mutant mice
The tumour suppressor gene, TES, is frequently methylated in many human tumours. Previously, we demonstrated that TES promoter methylation and transcriptional silencing was the most common molecular abnormality d...
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Article
The nonlinear association between outdoor temperature and cholesterol levels, with modifying effect of individual characteristics and behaviors
Few studies have been conducted to investigate the underlying mechanisms of the effect of temperature on cardiovascular disease at population level, especially among Chinese population. A total of 56,039 parti...
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Article
Open AccessDoes Bangkok have a central role in the dengue dynamics of Thailand?
Bangkok plays a central role in the commerce of Thailand. This study aimed to characterize the district-level spatial-temporal patterns of dengue in Thailand and explore if a dengue peak in Bangkok led the pea...
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Article
Open AccessSafety and neurochemical profiles of acute and sub-chronic oral treatment with agmatine sulfate
Agmatine (decarboxylated arginine) exerts numerous central nervous system (CNS) dependent pharmacological effects and may potentially modulate altered neurochemistry seen in neurological disorders. In preclini...
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Article
HIV Prevalence Among Tuberculosis Patients in Sub-Saharan Africa: A Systematic Review and Meta-analysis
HIV associated tuberculosis (TB) morbidity and mortality is a major concern in sub-Saharan Africa. Understanding the level of HIV infection among TB patients is vital for adequate response. We conducted a syst...
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Article
Law as Clinical Evidence: A New ConstitutiveModel of Medical Education and Decision-Making
Over several decades, ethics and law have been applied to medical education and practice in a way that reflects the continuation during the twentieth century of the strong distinction between facts and values....
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Open Access∆133p53 isoform promotes tumour invasion and metastasis via interleukin-6 activation of JAK-STAT and RhoA-ROCK signalling
∆122p53 mice (a model of ∆133p53 isoform) are tumour-prone, have extensive inflammation and elevated serum IL-6. To investigate the role of IL-6 we crossed ∆122p53 mice with IL-6 null mice. Here we show that loss...
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Open AccessComparing doctors’ legal compliance across three Australian states for decisions whether to withhold or withdraw life-sustaining medical treatment: does different law lead to different decisions?
Law purports to regulate end-of-life care but its role in decision-making by doctors is not clear. This paper, which is part of a three-year study into the role of law in medical practice at the end of life, i...
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Article
Does substantiated childhood maltreatment lead to poor quality of life in young adulthood? Evidence from an Australian birth cohort study
To examine the independent effect of single and multiple forms of substantiated childhood maltreatment (CM) on quality of life (QoL), controlling for selected potential confounders and/or covariates, and concu...
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Article
Open AccessGender differences in hypertension awareness, antihypertensive use and blood pressure control in Bangladeshi adults: findings from a national cross-sectional survey
Bangladesh is facing an epidemiological transition with a growing burden of non-communicable diseases. Traditionally, hypertension and associated complications in women receive less recognition, and there is a...
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Article
Open AccessSpatial and space–time distribution of Plasmodium vivax and Plasmodium falciparum malaria in China, 2005–2014
Despite the declining burden of malaria in China, the disease remains a significant public health problem with periodic outbreaks and spatial variation across the country. A better understanding of the spatial...
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Article
Open AccessGender differences in the prospective association between maternal alcohol consumption trajectories and young adult offspring’s problem gambling at 30 years
Although a large number of studies have examined the association between young adult’s alcohol consumption and their problem gambling behaviours, none of these studies address the prospective association betwe...
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Open AccessOutdoor Temperature, Heart Rate and Blood Pressure in Chinese Adults: Effect Modification by Individual Characteristics
We collected data from Kailuan cohort study from 2006 to 2011 to examine whether short-term effects of ambient temperature on heart rate (HR) and blood pressure (BP) are non-linear or linear, and their potenti...
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Article
Open AccessEl Niño-Southern Oscillation, local weather and occurrences of dengue virus serotypes
Severe dengue fever is usually associated with secondary infection by a dengue virus (DENV) serotype (1 to 4) that is different to the serotype of the primary infection. Dengue outbreaks only occur following i...
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Open AccessRapid growth in early childhood associated with young adult overweight and obesity – evidence from a community based cohort study
Rapid weight gain in early life may increase the risk of overweight and obesity in adulthood. We investigated the association between the rate of growth during early childhood and the development of overweight...
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The association between ambient temperature and children’s lung function in Baotou, China
The objective of this study is to examine the association between ambient temperature and children’s lung function in Baotou, China. We recruited 315 children (8–12 years) from Baotou, China in the spring of 2...
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Article
Trajectories and Predictors of Women’s Depression Following the Birth of an Infant to 21 Years: A Longitudinal Study
Little is known about the long-term mental health of women following the birth of an infant. This study describes the 21 year trajectory of women’s depression following the birth of an infant and identifies ea...
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Article
Synthesis, physiochemical characterization, and biocompatibility of a chitosan/dextran-based hydrogel for postsurgical adhesion prevention
An amine-functionalized succinyl chitosan and an oxidized dextran were synthesized and mixed in aqueous solution to form an in situ chitosan/dextran injectable, surgical hydrogel for adhesion prevention. Rheol...
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Open AccessThe association between air pollution and mortality in Thailand
Bayesian statistical inference with a case-crossover design was used to examine the effects of air pollutants {Particulate matter <10 μm in aerodynamic diameter (PM10), sulphur dioxide (SO2) and ozone (O3)} on mo...