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    NAD+ cellular redox and SIRT1 regulate the diurnal rhythms of tyrosine hydroxylase and conditioned cocaine reward

    The diurnal regulation of dopamine is important for normal physiology and diseases such as addiction. Here we find a novel role for the CLOCK protein to antagonize CREB-mediated transcriptional activity at the...

    Ryan W. Logan, Puja K. Parekh, Gabrielle N. Kaplan… in Molecular Psychiatry (2019)