8 Result(s)

Article

External quality assessment of HIV-1 DNA quantification assays used in the clinical setting in Italy

Total cell-associated HIV-1 DNA is a surrogate marker of the HIV-1 reservoir, however, certified systems for its quantification are not available. The Italian HIV DNA Network was launched to validate HIV-1 DNA...

Ilaria Vicenti, Filippo Dragoni, Alessia Giannini, Anna Casabianca… in Scientific Reports (2022)

Article

Analysis of HIV quasispecies and virological outcome of an HIV D+/R+ kidney–liver transplantation

Transplantation among HIV positive patients may be a valuable therapeutic intervention. This study involves an HIV D+/R+ kidney–liver transplantation, where PBMC-associated HIV quasispecies were analyzed in do...

Gabriella Rozera, Ubaldo Visco-Comandini, Emanuela Giombini… in Virology Journal (2022)

Article

Multi-omics approach to COVID-19: a domain-based literature review

Omics data, driven by rapid advances in laboratory techniques, have been generated very quickly during the COVID-19 pandemic. Our aim is to use omics data to highlight the involvement of specific pathways, as ...

Chiara Montaldo, Francesco Messina, Isabella Abbate… in Journal of Translational Medicine (2021)

Article

Iron overload down-regulates the expression of the HIV-1 Rev cofactor eIF5A in infected T lymphocytes

Changes in iron metabolism frequently accompany HIV-1 infection. However, while many clinical and in vitro studies report iron overload exacerbates the development of infection, many others have found no corre...

Carmine Mancone, Alessio Grimaldi, Giulia Refolo, Isabella Abbate… in Proteome Science (2017)

Article

HCV full-length genome reconstruction with sequence independent amplification combined with next generation sequencing

Barbara Bartolini, Emanuela Giombini, Isabella Abbate… in Retrovirology (2012)

Article

Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing

Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-novo sequencing, re-sequencing, meta-genomi...

Mattia CF Prosperi, Luciano Prosperi, Alessandro Bruselles… in BMC Bioinformatics (2011)

Article

Co-receptor usage prediction at quasispecies level using ultra-deep pyrosequencing on both circulating and proviral hiv in patients candidates to CCR5 antagonist treatment

Isabella Abbate, Gabriella Rozera, Chiara Tommasi, Alessandro Bruselles… in Retrovirology (2010)

Article

Massively parallel pyrosequencing highlights minority variants in the HIV-1 env quasispecies deriving from lymphomonocyte sub-populations

Virus-associated cell membrane proteins acquired by HIV-1 during budding may give information on the cellular source of circulating virions. In the present study, by applying immunosorting of the virus and of ...

Gabriella Rozera, Isabella Abbate, Alessandro Bruselles, Crhysoula Vlassi… in Retrovirology (2009)