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Article
Open AccessDetection of recombinant breakpoint in the genome of human enterovirus E11 strain associated with a fatal nosocomial outbreak
The aim of this study was to characterize the genome of a recombinant Enterovirus associated with severe and fatal nosocomial infection; it was typed as Echovirus 11 (E-11) according to the VP1 gene. Enterovir...
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Article
Open AccessAnalysis of HIV quasispecies and virological outcome of an HIV D+/R+ kidney–liver transplantation
Transplantation among HIV positive patients may be a valuable therapeutic intervention. This study involves an HIV D+/R+ kidney–liver transplantation, where PBMC-associated HIV quasispecies were analyzed in do...
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Article
Open AccessMulti-omics approach to COVID-19: a domain-based literature review
Omics data, driven by rapid advances in laboratory techniques, have been generated very quickly during the COVID-19 pandemic. Our aim is to use omics data to highlight the involvement of specific pathways, as ...
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Article
Open AccessLooking for pathways related to COVID-19: confirmation of pathogenic mechanisms by SARS-CoV-2–host interactome
In the last months, many studies have clearly described several mechanisms of SARS-CoV-2 infection at cell and tissue level, but the mechanisms of interaction between host and SARS-CoV-2, determining the grade...
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Article
Open AccessCOVID-19: viral–host interactome analyzed by network based-approach model to study pathogenesis of SARS-CoV-2 infection
Epidemiological, virological and pathogenetic characteristics of SARS-CoV-2 infection are under evaluation. A better understanding of the pathophysiology associated with COVID-19 is crucial to improve treatmen...
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Article
Analysis of hepatitis B virus-mixed genotype infection by ultra deep pyrosequencing in Sudanese patients, 2015–2016
The frequency of detection of HBV co-infection with multiple HBV genotypes is influenced by the detection method; usually co-infections are detected by multiplex PCR or hybridization assays, and are rarely co...
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Article
Open AccessHCV full-length genome reconstruction with sequence independent amplification combined with next generation sequencing
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Article
Open AccessAn automatic method for identifying surface proteins in bacteria: SLEP
Bacterial infections represent a global health challenge. The identification of novel antibacterial targets for both therapy and vaccination is needed on a constant basis because resistance continues to spread...
