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  1. No Access

    Chapter and Conference Paper

    Astrocytes co-express aquaporin-1, -4, and vascular endothelial growth factor in brain edema tissue associated with brain contusion

    Brain edema may be life threatening. The mechanisms underlying the development of traumatic brain edema are still unclear; however, mixed mechanisms including vasogenic, ischemic, and neurotoxic types of edema...

    R. Suzuki, M. Okuda, J. Asai, G. Nagashima, H. Itokawa, A. Matsunaga… in Brain Edema XIII (2006)

  2. No Access

    Article

    P53 Overexpression and Proliferative Potential in Malignant Meningiomas

     Meningiomas are generally benign, but some meningiomas show malignancy with invasion and high recurrence rates. We investigated whether alterations in p53 protein may contribute to malignant progression in me...

    G. Nagashima, M. Aoyagi, M. Yamamoto, S. Yamamoto, H. Wakimoto… in Acta Neurochirurgica (1999)

  3. No Access

    Chapter and Conference Paper

    Modulation of Protein Synthesis and Calcium Uptake Following Traumatic Lesion of Rat Brain Cortex

    Following cold lesion of rat brain cortex, the time course of regional cerebral protein synthesis (CSP) and cerebral calcium uptake (CCU) was assessed in the same animal using [3H]leucine and 45CaCl by means of d...

    G. Mies, N. Kawahara, K. Kawai, G. Nagashima… in Maturation Phenomenon in Cerebral Ischemia… (1997)

  4. No Access

    Chapter and Conference Paper

    Possible Role of Intracellular Calcium Translocation in the Maturation of Ischemic Damage

    The fine structural localization of calcium was studied in 3-month-old female Mongolian gerbils (Meriones unguiculatus) subjected to single 5-min bilateral common carotid artery occlusions. Intracellular calcium ...

    F. Joó, J. Ikeda, J. Lohr, G. Nagashima… in Maturation Phenomenon in Cerebral Ischemia (1992)

  5. No Access

    Chapter and Conference Paper

    Protein Synthesis and Calcium Uptake Following Complete Cerebral Ischemia of Rat Brain

    The possible involvement of neuroexcitatory pathomechanisms in the development of postischemic neuron injury was examined in rats subjected to 10-min cardiac arrest for the induction of complete cerebral ische...

    G. Mies, K. Kawai, N. Saito, G. Nagashima… in Maturation Phenomenon in Cerebral Ischemia (1992)

  6. No Access

    Chapter and Conference Paper

    Role of Neuroexcitation in Development of Blood-Brain Barrier and Oedematous Changes Following Cerebral Ischaemia and Traumatic Brain Injury

    Potential involvement of neuroexcitatory mechanisms was studied in: 1) repetitive forebrain ischaemia in gerbils, 2) global cerebral ischaemia in rats and 3) cryogenic injury to the cerebral cortex in rats and...

    N. Saito, C. Chang, K. Kawai, F. Joó, T. S. Nowak Jr., G. Mies… in Brain Edema VIII (1990)