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Article
Open AccessEngraftment and morphological development of vascularized human iPS cell-derived 3D-cardiomyocyte tissue after xenotransplantation
One of the major challenges in cell-based cardiac regenerative medicine is the in vitro construction of three-dimensional (3D) tissues consisting of induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) a...
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Article
Interaction between living cells and polymeric particles: potential application of ionic liquid for evaluating the cellular uptake of biodegradable polymeric particles composed of poly(amino acid)
The cellular uptake of biodegradable particles as drug or vaccine carriers was observed by scanning electron microscopy employing an ionic liquid. The samples were observed by simply dip** them into the ioni...
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Article
Synthesis and preparation of nanoparticles composed of amphiphilic poly(γ-glutamic acid) with different hydrophobic side chains and their potential of membrane disruptive activity
In the development of nanoparticle-based vaccine adjuvants, the interaction between nanoparticles (NPs) and the cells is a key factor. To control them, we focused on the relationship between the hydrophobicity...
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Article
Preparation of microparticles composed of amphiphilic poly(γ-glutamic acid) through hydrophobic interactions
A novel amphiphilic graft copolymer composed of poly(γ-glutamic acid) (γ-PGA) as a hydrophilic backbone and dodecylamine (DOA) as a hydrophobic side chain (γ-PGA-DOA) was successfully synthesized by employing ...
