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Waking Up Brain with Electrical Stimulation to Boost Memory in Sleep: A Neuroscience Exploration
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Identification and Experimental Validation of Parkinson’s Disease with Major Depressive Disorder Common Genes
Parkinson’s disease (PD) is the second most common neurodegenerative disease that affects about 10 million people worldwide. Non-motor and motor symptoms usually accompany PD. Major depressive disorder (MDD) i...
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Article
Open AccessSNHG15 is a negative regulator of inflammation by mediating TRAF2 ubiquitination in stroke-induced immunosuppression
Abnormal expression of long noncoding RNAs (lncRNAs) has been reported in the acute stage of acute ischemic stroke (AIS). This study aimed to explore differential lncRNA expression in the subpopulations of per...
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Article
Open AccessDown-regulation of circular RNA CDC14A peripherally ameliorates brain injury in acute phase of ischemic stroke
Inflammation is integral to the pathophysiology of ischemic stroke and a prime target for the development of new stroke therapies. The aim of the present study is to seek out the regulatory mechanism of circCD...
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Article
Structure-Based Optimization of Therapeutic Peptide Selectivity Between Cerebrovascular Rho-1 and Rho-2 Kinase Isoforms
The cerebrovascular Rho kinase pathway has been implicated in the pathogenesis of central nervous system disorders, which is regulated by two highly homologous isoforms Rho-1 and Rho-2. Selective targeting of ...
