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  1. No Access

    Article

    Occurrence of chemical pollutants in major e-waste sites in West Africa and usefulness of cytotoxicity and induction of ethoxyresorufin-O-deethylase (EROD) in determining the effects of some detected brominated flame retardants and e-waste soil-derived extracts

    We investigated the occurrence of chemical pollutants in major e-waste sites in West Africa and usefulness of cytotoxicity and induction of ethoxyresorufin-O-deethylase (EROD) in determining the effects of some d...

    Chukwuebuka ThankGod Eze… in Environmental Science and Pollution Resear… (2021)

  2. Article

    Open Access

    Neferine induces autophagy-dependent cell death in apoptosis-resistant cancers via ryanodine receptor and Ca2+-dependent mechanism

    Resistance of cancer cells to chemotherapy is a significant clinical concern and mechanisms regulating cell death in cancer therapy, including apoptosis, autophagy or necrosis, have been extensively investigat...

    Betty Yuen Kwan Law, Francesco Michelangeli, Yuan Qing Qu, Su-Wei Xu… in Scientific Reports (2019)

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  3. Article

    Open Access

    (Z)3,4,5,4′-trans-tetramethoxystilbene, a new analogue of resveratrol, inhibits gefitinb-resistant non-small cell lung cancer via selectively elevating intracellular calcium level

    Calcium is a second messenger which is required for regulation of many cellular processes. However, excessive elevation or prolonged activation of calcium signaling would lead to cell death. As such, selective...

    **ng-**ng Fan, **ao-Jun Yao, Su Wei Xu, Vincent Kam-Wai Wong… in Scientific Reports (2015)

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  4. No Access

    Article

    Commonly used ryanodine receptor activator, 4-chloro-m-cresol (4CmC), is also an inhibitor of SERCA Ca2+ pumps

    4-Chloro-m-cresol (4CmC) is an extensively used activator of ryanodine receptors (RyRs). Studies have shown that 4CmC, at a concentration of 1 mM, is sufficient to cause Ca2+ release through RyRs. Here, we show t...

    Fawaz Al-Mousa, Francesco Michelangeli in Pharmacological Reports (2009)

  5. Article

    Open Access

    Enzymatic method for assaying calcium in serum with Ca++-ATPase

    A kinetic assay for total calcium in serum was developed which is based on the activation of Ca++-ATPase by free Ca++ [Ca++]f maintained by EGTA in the reaction mixture. The concentration of Caf++ was dependent o...

    Masood-ul-Hassan Javed, Francesco Michelangeli in Experimental & Molecular Medicine (2003)

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  6. No Access

    Article

    Opening up Ca2+ stores with lnsP3

    Mokdad Mezna, Francesco Michelangeli in Nature (1995)

  7. No Access

    Article

    Measuring calcium uptake and inositol 1,4,5-trisphosphate-induced calcium release in cerebellum microsomes using Fluo-3

    A simple fluorimetric method is presented for measuring calcium uptake and inositol 1,4,5-trisphosphate (InsP3)-induced calcium release in microsomes using Fluo-3. This method is used to investigate the amplitude...

    Francesco Michelangeli in Journal of Fluorescence (1991)