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Article

A Novel Methodology to Estimate the Treatment Effect in Presence of Highly Variable Placebo Response

One of the main reasons for the inefficiency of multicenter randomized clinical trials (RCTs) in depression is the excessively high level of placebo response. The aim of this work was to propose a novel method...

Roberto Gomeni, Navin Goyal, Françoise Bressolle, Maurizio Fava in Neuropsychopharmacology (2015)