14 Result(s)

Article

Prone position in wards for spontaneous breathing Covid-19 patients: a retrospective study

The pandemic of coronavirus disease 2019 (Covid-19) caused a large number of non-ventilated hypoxemic patients to require the use of prone position. The aim of this study is to measure the efficiency and toler...

Johan Wormser, Christophe Romanet… in Irish Journal of Medical Science (1971 -) (2021)

Article

Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric)

Emerging resistance to antibiotics shows no signs of decline. At the same time, few new antibacterials are being discovered. There is a worldwide recognition regarding the danger of this situation. The urgency...

Cédric Bretonnière, Marc Leone, Christophe Milési… in Intensive Care Medicine (2015)

Article

Stratégies de réduction de l’utilisation des antibiotiques à visée curative en réanimation (adulte et pédiatrique)

Jean-Pierre Bédos, Bernard Allaouchiche, Laurence Armand-Lefèvre… in Réanimation (2014)

Article

Role of biomarkers in the management of antibiotic therapy: an expert panel review: I – currently available biomarkers for clinical use in acute infections

In the context of worldwide increasing antimicrobial resistance, good antimicrobial prescribing in more needed than ever; unfortunately, information available to clinicians often are insufficient to rely on. B...

Anne-Marie Dupuy, François Philippart, Yves Péan… in Annals of Intensive Care (2013)

Article

Role of biomarkers in the management of antibiotic therapy: an expert panel review II: clinical use of biomarkers for initiation or discontinuation of antibiotic therapy

Biomarker-guided initiation of antibiotic therapy has been studied in four conditions: acute pancreatitis, lower respiratory tract infection (LRTI), meningitis, and sepsis in the ICU. In pancreatitis with susp...

Jean-Pierre Quenot, Charles-Edouard Luyt, Nicolas Roche… in Annals of Intensive Care (2013)

Article

Phenomenologic analysis of healthcare worker perceptions of intensive care unit diaries

Studies have reported associations between diaries kept for intensive care unit (ICU) patients and long-term quality-of-life and psychological outcomes in patients and their relatives. Little was known about p...

Antoine Perier, Anne Revah-Levy, Cédric Bruel, Nathalie Cousin… in Critical Care (2013)

Article

Toll-like receptors expression and interferon-γ production by NK cells in human sepsis

During the course of infection, natural killer (NK) cells contribute to innate immunity by producing cytokines, particularly interferon-gamma (IFN-γ). In addition to their beneficial effects against infection,...

Fernando Souza-Fonseca-Guimaraes, Marianna Parlato, François Philippart… in Critical Care (2012)

Article

Overview of medical errors and adverse events

Safety is a global concept that encompasses efficiency, security of care, reactivity of caregivers, and satisfaction of patients and relatives. Patient safety has emerged as a major target for healthcare impro...

Maité Garrouste-Orgeas, François Philippart, Cédric Bruel… in Annals of Intensive Care (2012)

Article

In vivo bioluminescence imaging and histopathopathologic analysis reveal distinct roles for resident and recruited immune effector cells in defense against invasive aspergillosis

Invasive aspergillosis (IA) is a major cause of infectious morbidity and mortality in immune compromised patients. Studies on the pathogenesis of IA have been limited by the difficulty to monitor disease progr...

Oumaïma Ibrahim-Granet, Grégory Jouvion, Tobias M Hohl… in BMC Microbiology (2010)

Article

Sepsis mediators

During sepsis, the plasma levels of numerous inflammatory markers are enhanced. Some of these markers are the mediators responsible for the syndromes observed during sepsis as well as for organ dysfunction and...

François Philippart, Jean-Marc Cavaillon in Current Infectious Disease Reports (2007)