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    RNA substrate binding site in the catalytic core of the Tetrahymena ribozyme

    In catalysis by group I introns, the helix (P1) containing the RNA cleavage site must be positioned next to the guanosine binding site. We have identified a conserved adenine in the catalytic core that contrib...

    Anna Marie Pyle, Felicia L. Murphy, Thomas R. Cech in Nature (1992)