6 Result(s)

Article

FOXP3 recognizes microsatellites and bridges DNA through multimerization

FOXP3 is a transcription factor that is essential for the development of regulatory T cells, a branch of T cells that suppress excessive inflammation and autoimmunity^1–5. However, the molecular mechanisms of FOXP...

Wenxiang Zhang, Fangwei Leng, ** Wang, Ricardo N. Ramirez, **seok Park… in Nature (2023)

Article

NLRP6 self-assembles into a linear molecular platform following LPS binding and ATP stimulation

NOD-like receptors (NLRs) localize in the cytosol to recognize intracellular pathogen products and initialize the innate immune response. However, the ligands and ligand specificity of many NLRs remain unclear...

Fangwei Leng, Hang Yin, Siying Qin, Kai Zhang, Yukun Guan, Run Fang… in Scientific Reports (2020)

Article

Build a two-way road for health industry: the current circumstance of translational medicine in China

FangWei Leng in Science China Life Sciences (2012)

Article

Opportunity and challenge: ten years of proteomics in China

FangWei Leng in Science China Life Sciences (2012)

Article

On Ca²⁺ signalling research

FangWei Leng in Science China Life Sciences (2012)

Article

Recent progress of immunology research in China

FangWei Leng in Science China Life Sciences (2011)