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Article
Improved slagging characteristics of low-value solid waste fuel asphalt rock by mineral additives of CaCO3, MgO, and Kaolin under fluidized bed condition
As a low-value solid waste fuel, asphalt rock is prone to slagging even under fluidized bed condition. The purpose of this study is to improve the slagging characteristics of asphalt rock by adding the mineral...
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Article
CCDC92 promotes podocyte injury by regulating PA28α/ABCA1/cholesterol efflux axis in type 2 diabetic mice
Podocyte lipotoxicity mediated by impaired cellular cholesterol efflux plays a crucial role in the development of diabetic kidney disease (DKD), and the identification of potential therapeutic targets that reg...
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Article
Structure of GPR101–Gs enables identification of ligands with rejuvenating potential
GPR101 is an orphan G protein-coupled receptor actively participating in energy homeostasis. Here we report the cryo-electron microscopy structure of GPR101 constitutively coupled to Gs heterotrimer, which rev...
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Article
Open AccessStudy of the mechanism by gentiopicroside protects against skin fibroblast glycation damage via the RAGE pathway
The occurrence of nonenzymatic glycosylation reactions in skin fibroblasts can lead to severe impairment of skin health. To investigate the protective effects of the major functional ingredient from Gentianace...
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Chapter and Conference Paper
Study About the Surface Charge Accumulation and Dissipation of Insulators Under Corona Condition
The insulator surface charge buildup issue is a significant element impacting the electric field on the insulator surface in HVDC transmission. The electrostatic probe method is used to measure the surface pot...
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Article
Water Resource Surveillance for the Salton Sea in California By Adaptive Sequential Monitoring of Its Landsat Images
Gradual loss of water resource in the Salton Sea has got much attention from researchers recently for its damage to the local environment and ecosystems for human beings, animals and plants. To monitor the wat...
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Article
Open AccessTargeting oxidative stress as a preventive and therapeutic approach for cardiovascular disease
Cardiovascular diseases (CVDs) continue to exert a significant impact on global mortality rates, encompassing conditions like pulmonary arterial hypertension (PAH), atherosclerosis (AS), and myocardial infarct...
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Article
The abrogation of GRP78 sensitizes liver cancer cells to lysionotin by enhancing ER stress-mediated pro-apoptotic pathway
Glucose-regulated protein 78 (GRP78) is frequently and highly expressed in various human malignancies and protects cancer cells against apoptosis induced by multifarious stresses, particularly endoplasmic reti...
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Article
GPR97 deficiency ameliorates renal interstitial fibrosis in mouse hypertensive nephropathy
Hypertensive nephropathy (HTN) ranks as the second-leading cause of end-stage renal disease (ESRD). Accumulating evidence suggests that persistent hypertension injures tubular cells, leading to tubulointerstit...
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Article
Organic geochemical characteristics and organic matter accumulation of the Eocene lacustrine source rock in the Yingxi area, Western Qaidam Basin, China
The lacustrine source rocks of the upper member of the lower Ganchaigou Formation ( \({\text{E}}_{3}^{2}\) ...
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Article
Open AccessActivating the Hippo pathway by nevadensin overcomes Yap-drived resistance to sorafenib in hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a highly malignant type of tumor that is insensitive to cytotoxic chemotherapy and often develops drug resistance. Nevadensin, a bioflavonoid, exhibits anti-cancer properties ...
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Article
Open AccessHDAC9-mediated epithelial cell cycle arrest in G2/M contributes to kidney fibrosis in male mice
Renal tubular epithelial cells (TECs) play a key role in kidney fibrosis by mediating cycle arrest at G2/M. However, the key HDAC isoforms and the underlying mechanism that are involved in G2/M arrest of TECs ...
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Article
Open AccessTargeting pyroptosis as a preventive and therapeutic approach for stroke
Stroke has caused tremendous social stress worldwide, yet despite decades of research and development of new stroke drugs, most have failed and rt-PA (Recombinant tissue plasminogen activator) is still the acc...
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Article
Approaching 19% efficiency and stable binary polymer solar cells enabled by a solidification strategy of solvent additive
Additives play a crucial role in enhancing the photovoltaic performance of polymer solar cells (PSCs). However, the typical additives used to optimize blend morphology of PSCs are still high boiling-point solv...
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Article
Open AccessSystemic inflammation indicators and risk of incident arrhythmias in 478,524 individuals: evidence from the UK Biobank cohort
The role of systemic inflammation in promoting cardiovascular diseases has attracted attention, but its correlation with various arrhythmias remains to be clarified. We aimed to comprehensively assess the asso...
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Article
Open AccessThe mechanism of programmed death and endoplasmic reticulum stress in pulmonary hypertension
Pulmonary hypertension (PH) was a cardiovascular disease with high morbidity and mortality. PH was a chronic disease with complicated pathogenesis and uncontrollable factors. PH was divided into five groups ac...
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Article
Pelive Floor Myofascisl Therapy is Associated with Improved VAS Pain Scores and FSFI Scores in Women with Dyspareunia 6 Months Post-partum
The incidence of dyspareunia at 6 months post-partum is very high. However, effective treatments are limited. Pelvic floor myofascial therapy is a useful method, we investigated the efficacy of it. 72 post-par...
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Article
A review: development of named entity recognition (NER) technology for aeronautical information intelligence
The rapid development of data and artificial intelligence technology has introduced new opportunities and challenges to aeronautical information intelligence. However, there are many obstacles in the sharing, ...
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Chapter and Conference Paper
Research on Fast Extraction Method of Resistive Current of 500 kV Arrester Based on Field Circuit Coupling
The proportion of resistive current in the leakage current of lightning arrester is very small, and it is difficult to judge the health state of lightning arrester directly by the leakage current in the degrad...
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Article
Preparation of curcumin stabilized pigment coated by zeolitic imidazolate framework material ZIF-8
In order to solve the problems of instability, easy hydrolysis and low dyeing efficiency of curcumin during storage and dyeing, the zeolite imidazolate framework material ZIF-8 was used as a carrier to coat cu...
