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Article
Open AccessEffects of Android phone vs. iPhone use on BlackBerry thumb symptoms among university students in Bangladesh
In Bangladesh, the most prevalent musculoskeletal condition among office employees is considered as BlackBerry thumb (BBT). Alike official perspectives, our educational system was significantly regulating with...
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Article
Open AccessParathyroid hormone (1–34) retards the lumbar facet joint degeneration and activates Wnt/β-catenin signaling pathway in ovariectomized rats
Facet joint degeneration (FJD) is a major cause of low back pain. Parathyroid hormone (PTH) (1–34) is commonly used to treat osteoporosis. However, little is known about its effects on FJD induced by estrogen ...
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Article
Open AccessExpression of lncRNA LINC00943 in lung squamous cell carcinoma and its relationship with tumor progression
Molecular biology has been applied to the diagnosis, prognosis and treatment of various diseases, and long noncoding RNA LINC00943 (lncRNA LINC00943; LINC00943) plays an important role in a variety of cancers....
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Article
Open AccessEffects of alendronate on cartilage lesions and micro-architecture deterioration of subchondral bone in patellofemoral osteoarthritic ovariectomized rats with patella-baja
Patellofemoral osteoarthritis (PFJOA) is a subtype of knee OA, which is one of the main causes of anterior knee pain. The current study found an increased prevalence of OA in postmenopausal women, called postm...
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Article
Open AccessEstrogen deficiency impedes fracture healing despite eliminating the excessive absorption of the posterior callus in a semi-fixed distal tibial fracture mouse model
Treatment of distal tibial fractures is a challenge due to their specific anatomical location. However, there is no appropriate mouse model to simulate a clinical distal tibial fracture for basic research. The...
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Article
Open AccessNew-onset stroke on the risk of hip fracture: the Kailuan cohort study in China
Stroke is a documented risk factor for hip fracture(HF). However, no data is currently available on this issue in mainland China, we therefore assessed the risk of hip fracture after new-onset stroke using a c...
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Article
Open AccessThe role of wnt signaling in diabetes-induced osteoporosis
Osteoporosis, a chronic complication of diabetes mellitus, is characterized by a reduction in bone mass, destruction of bone microarchitecture, decreased bone strength, and increased bone fragility. Because of...
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Article
Open AccessSTAT3-mediated osteogenesis and osteoclastogenesis in osteoporosis
Osteoporosis is a common skeletal disease with marked bone loss, deterioration of the bone microstructure and bone fragility. An abnormal bone remodelling cycle with relatively increased bone resorption is the...
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Article
Parathyroid Hormone (1–34) Attenuates Cartilage Degradation and Preserves Subchondral Bone Micro-architecture in Rats with Patella Baja-Induced-Patellofemoral Joint Osteoarthritis
Several studies have revealed that PTH1-34 may possess the potential for treating osteoarthritis (OA) and osteoporosis. However, no study has yet determined whether PTH1-34 can be used for the treatment of pat...
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Article
Keratin/PEO/hydroxyapatite Nanofiber Membrane with Improved Mechanical Property for Potential Burn Dressing Application
Keratin, as a promising substitute for tissue engineering due to its excellent biocompatibility and bioactivity, is used to combine one or more other polymers together. However, compound nanofibers with high k...
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Article
Open AccessWnt signaling: a promising target for osteoarthritis therapy
Osteoarthritis (OA) is the most common joint disease worldwide and a leading cause of disability. Characterized by degradation of articular cartilage, synovial inflammation, and changes in periarticular and su...
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Article
Open AccessPoint-of-care measurements reveal release of purines into venous blood of stroke patients
Stroke is a leading cause of death and disability. Here, we examine whether point-of-care measurement of the purines, adenosine, inosine and hypoxanthine, which are downstream metabolites of ATP, has potential...
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Article
Open AccessThe association between early neurological deterioration and whole blood purine concentration during acute stroke
Early neurological deterioration (END) is common after stroke. Prediction could identify patients requiring additional monitoring and intervention. Purines, breakdown products of adenosine triphosphate which a...
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Article
Open AccessBlood purine measurements as a rapid real-time indicator of reversible brain ischaemia
To preserve the disequilibrium between ATP and ADP necessary to drive cellular metabolism, enzymatic pathways rapidly convert ADP to adenosine and the downstream purines inosine and hypoxanthine. During ischae...
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Protocol
Hexacyanoferrates as Mediators for Microelectrode Biosensors
Hexacyanoferrates such as Prussian blue or Ruthenium Purple have great potential for use in microelectrode biosensors. They act as surface-bound mediators that greatly facilitate the detection of H2O2 at modest p...
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Article
Enhancement of subchondral bone quality by alendronate administration for the reduction of cartilage degeneration in the early phase of experimental osteoarthritis
To evaluate the effects of alendronate (ALN) on the subchondral bone quality and cartilage degeneration in the early phase of experimental model of osteoarthritis after anterior cruciate ligament transaction (...
