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Article
LHAASO-KM2A detector simulation using Geant4
KM2A is one of the main sub-arrays of LHAASO, working on gamma ray astronomy and cosmic ray physics at energies above 10 TeV. Detector simulation is the important foundation for estimating detector performance...
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Article
Radial nonlinear vibrations of thin-walled hyperelastic cylindrical shell composed of Mooney–Rivlin materials under radial harmonic excitation
In this paper, the radial nonlinear vibrations are investigated for a thin-walled hyperelastic cylindrical shell composed of the classical incompressible Mooney–Rivlin materials subjected to a radial harmonic ...
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Article
Age-related adiposity and beta-cell function: impact on prediabetes and diabetes prevalence in middle-aged and older Han Chinese adults
To investigate the effect of aging on the prevalence of prediabetes and diabetes, and the influence of aging on the associations among adipose mass, redistribution, β cell function, and the prevalence of hyper...
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Article
Reconstruction of Cherenkov image by multiple telescopes of LHAASO-WFCTA
One of main scientific goals of the Large High Altitude Air Shower Observatory (LHAASO) is to accurately measure the energy spectra of different cosmic ray compositions around the ‘knee’ region. The Wide Field...
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Article
A dynamic range extension system for LHAASO WCDA-1
The main scientific goal of LHAASO-WCDA is to survey gamma-ray sources with energy from 100 GeV to 30 TeV. To observe high-energy shower events, especially to measure the energy spectrum of cosmic rays from 10...
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Article
Line-of-shower trigger method to lower energy threshold for GRB detection using LHAASO-WCDA
Observation of high energy and very high emission from Gamma Ray Bursts (GRBs) is crucial to study the gigantic explosion and the underline processes. With a large field-of-view and almost full duty cycle, the...
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Article
Successful TAMIS in an elderly patient with a large rectal adenoma
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Article
Open AccessConstruction and on-site performance of the LHAASO WFCTA camera
The focal plane camera is the core component of the Wide Field-of-view Cherenkov/fluorescence Telescope Array (WFCTA) of the Large High-Altitude Air Shower Observatory (LHAASO). Because of the capability of wo...
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Article
Ultrahigh-energy photons up to 1.4 petaelectronvolts from 12 γ-ray Galactic sources
The extension of the cosmic-ray spectrum beyond 1 petaelectronvolt (PeV; 1015 electronvolts) indicates the existence of the so-called PeVatrons—cosmic-ray factories that accelerate particles to PeV energies. We n...
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Article
Mid-Deep and Deeply Buried Clastic Reservoirs Porosity Evolution Simulation with Using the Process-Based Method
It was showed that reservoir diagenetic and reservoir-forming characteristics are of great value for exploration and exploitation of conventional and unconventional reservoirs. Thus understanding on diagenetic...
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Article
Does complexity relate to compensation? A comparison of relative value units in initial versus recurrent inguinal hernia repair
Work relative value units (wRVUs) can be used as a compensation model based on the effort required for providing a service and helps to determine adequate compensation for physicians. Thus, more complex surgic...
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Article
Role of TIM-3 in ovarian cancer
Evidences have suggested that immunotherapy for ovarian cancer is effective. Immune checkpoints have emerged in the field of cancer immunotherapy. Multiple studies have shown negative regulation of TIM-3 expre...
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Article
Embelin attenuates adipogenesis and lipogenesis through activating canonical Wnt signaling and inhibits high-fat diet-induced obesity
Recent studies suggest that Embelin, a natural plant extract might have the potential to prevent body weight gain in rats. However, the mechanisms involved remain to be elucidated.
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Article
Kinetic study of titanium-bearing electric arc furnace molten slag treated by molten sodium hydroxide
In the present work, we investigate the effects of roasting temperature and time on the transformation of the titanium (Ti)-bearing phase and magnesium aluminate spinel (MgAl2O4) phase in Ti-bearing electric arc ...
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Article
Quenching and Partitioning of Ultrahigh Carbon (1.69 Mass% C) Steel
Quenching and partitioning (Q&P) or quenching and tempering (Q&T) process of modified ultrahigh carbon steel (UHCS, Fe–1.69C–1.38Si–1.84Mn–2.20Cr–0.54Mo–0.43Ni wt%) was investigated by means of scanning electr...
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Article
Open AccessOverexpression of a glucokinase point mutant in the treatment of diabetes mellitus
Glucokinase (GCK) is an important enzyme critical for glucose metabolism, and has been targeted as such in the pursuit of a cure for diabetes mellitus. We show that streptozotocin (STZ)-induced diabetic murine...
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Article
Efficacy of bisphosphonates against osteoporosis in adult men: a meta-analysis of randomized controlled trials
This meta-analysis of published randomized controlled trials (RCTs) aimed to analyze the efficacy of administration of bisphosphonates in men with osteoporosis. Compared with placebo, bisphosphonates could red...
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Article
Thermal Shock and Ablation Behavior of Tungsten Nozzle Produced by Plasma Spray Forming and Hot Isostatic Pressing
Tungsten nozzle was produced by plasma spray forming (PSF, relative density of 86 ± 2%) followed by hot isostatic pressing (HI**, 97 ± 2%) at 2000 °C and 180 MPa for 180 min. Scanning electron microscope, x-...
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Article
miR-20a regulates adipocyte differentiation by targeting lysine-specific demethylase 6b and transforming growth factor-β signaling
Several types of microRNAs (miRNAs) have recently been defined as important regulators in adipocyte differentiation, the role of other miRNAs in the processes and the mechanisms involved remain to be explored.
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Article
Open AccessThe role of hypoxia-inducible factor-2 in digestive system cancers
Hypoxia is an all but ubiquitous phenomenon in cancers. Two known hypoxia-inducible factors (HIFs), HIF-1α and HIF-2α, primarily mediate the transcriptional response to hypoxia. Despite the high homology between ...
