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Article
B cells and tertiary lymphoid structures are associated with survival in papillary thyroid cancer
The function of B cells in papillary thyroid cancer (PTC) is controversial. The role of B-cell-related tertiary lymphoid structures (TLSs) is still unclear. Whether B cells exert their anti-tumor effect throug...
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Article
Strain-rate-dependent cohesive zone modelling of charge damage behavior when a projectile penetrates multilayered targets
The high impulsive overload when a projectile penetrates multilayered targets affects the performance of explosive charge, which is an important component of many weapons. A tensile stress wave is generated in...
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Article
Development and validation of a three-immune-related gene signature prognostic risk model in papillary thyroid carcinoma
Increasing evidence indicates that there is a correlation between papillary thyroid carcinoma (PTC) prognosis and the immune signature. Our goal was to construct a new prognostic tool based on immune genes to ...
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Article
Open AccessMeasurement of the central exclusive production of charged particle pairs in proton-proton collisions at \( \sqrt{s} \) = 200 GeV with the STAR detector at RHIC
We report on the measurement of the Central Exclusive Production of charged particle pairs h+h− (h = π, K, p) with the STAR detector at RHIC in proton-proton collisions at
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Article
Open AccessAspartate β-hydroxylase disrupts mitochondrial DNA stability and function in hepatocellular carcinoma
The mechanism of aberrant mitochondrial genome and function in hepatocellular carcinoma (HCC) remains largely unknown. Our previous study demonstrated an increased expression of aspartate β-hydroxylase (ASPH) ...
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Article
Cooperation among heterogeneous prostate cancer cells in the bone metastatic niche
The growth of disseminated tumor cells into metastatic lesions depends on the establishment of a favorable microenvironment in the stroma of the target organs. Here we show that mice treated with anakinra, an ...
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Article
Open AccessESICM LIVES 2016: part two
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Article
Serum uric acid may not be involved in the development of preeclampsia
Higher serum levels of uric acid are associated with preeclampsia and may signal an early change in preeclampsia. However there is less evidence suggesting there is a meaningful association between uric acid a...
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Article
Open AccessDevelopment of secondary mutations in wild-type and mutant EZH2 alleles cooperates to confer resistance to EZH2 inhibitors
The histone methyltransferase Enhancer of Zeste Homolog 2 (EZH2) is frequently dysregulated in cancers, and gain-of-function (GOF) EZH2 mutations have been identified in non-Hodgkin lymphomas. Small-molecule i...
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Article
Inhibition of pathological brain angiogenesis through systemic delivery of AAV vector expressing soluble FLT1
The soluble vascular endothelial growth factor (VEGF) receptor 1 (sFLT1) has been tested in both animals and humans for anti-angiogenic therapies, for example, age-related macular degeneration. We hypothesized...
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Article
An analysis of expectant management in women with early-onset preeclampsia in China
Preeclampsia is a pregnancy-specific disorder and a leading cause of morbidity and mortality in both women and fetus. Although women with early severe preeclampsia are generally considered to require expedious...
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Article
Is ethnicity a risk factor for develo** preeclampsia? An analysis of the prevalence of preeclampsia in China
Preeclampsia is a major complication of pregnancy. Risk factors for preeclampsia include population and regional ethnicity. Chinese women living outside the Chinese mainland have a lower prevalence of preeclam...
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Article
Open AccessGenetic variant predicts bevacizumab-induced hypertension in ECOG-5103 and ECOG-2100
Bevacizumab has broad anti-tumour activity, but substantial risk of hypertension. No reliable markers are available for predicting bevacizumab-induced hypertension.
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Article
Open AccessA nomogram predicting pulmonary metastasis of hepatocellular carcinoma following partial hepatectomy
Pulmonary metastasis (PM) following curative hepatectomy for hepatocellular carcinoma (HCC) is indicative of a poor prognosis. This study aimed to develop a nomogram to identify patients at high risks of PM.
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Article
Heat shock protein 27: a potential biomarker of peritoneal metastasis in epithelial ovarian cancer?
Ovarian cancer is the major gynaecologic malignancy and the leading cause of death in gynaecological cancer. Heat shock proteins (HSPs) are highly expressed in many malignant cancers and involved in metastasis...
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Article
Increased expression of Rab25 in breast cancer correlates with lymphatic metastasis
Breast cancer is the most common cancer in women worldwide. Studies have suggested that Ras-related protein 25 (Rab25), a member of Rab small GTPase family, is involved in the pathogenesis of breast cancer. In...
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Article
Differential Rotation of Strong Magnetic Flux During Solar Cycles 21 – 23
In the present investigation we measure the differential rotation of strong magnetic flux during solar cycles 21 – 23 with the method of wavelet transforms. We find that the cycle-averaged synodic rotation rat...
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Article
Variability of Extended Bipolar Regions
Using NSO/Kitt Peak synoptic charts from 1975 to 2003, we group the main solar magnetic fields into two categories: one for active regions (ARs) and the other for extended bipolar regions (EBRs). Comparing the...
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Article
Surgical complications secondary to decompressive craniectomy in patients with a head injury: a series of 108 consecutive cases
Decompressive craniectomy is an important method for managing refractory intracranial hypertension in patients with head injury. We reviewed a large series of patients who underwent this surgical procedure to ...
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Chapter and Conference Paper
Development of a cerebral microvascular dysplasia model in rodents
Normal vasculature development of the central nervous system is extremely important because patients with vascular malformations are at life-threatening risk for intracranial hemorrhage or cerebral ischemia. T...
