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    Article

    Vancomycin population pharmacokinetics for adult patients with sepsis or septic shock: are current dosing regimens sufficient?

    Vancomycin is commonly used for the management of severe infections; however, vancomycin dosing may be challenging in critically ill patients. This observational study aims to describe the population pharmacok...

    A. J. Heffernan, A. Germano, F. B. Sime in European Journal of Clinical Pharmacology (2019)

  2. Article

    Individualising Therapy to Minimize Bacterial Multidrug Resistance

    The scourge of antibiotic resistance threatens modern healthcare delivery. A contributing factor to this significant issue may be antibiotic dosing, whereby standard antibiotic regimens are unable to suppress ...

    A. J. Heffernan, F. B. Sime, J. Lipman, J. A. Roberts in Drugs (2018)