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Application of a Ball Milling Technique for the Condensation of Anthranilic Hydrazides with Aromatic Aldehydes Towards 4-Quinazolinone Derivatives*

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  1. Article

    Open Access

    Topical dura mater application of CFA induces enhanced expression of c-fos and glutamate in rat trigeminal nucleus caudalis: attenuated by KYNA derivate (SZR72)

    Migraine is a debilitating neurological disorder where trigeminovascular activation plays a key role. We have previously reported that local application of Complete Freund’s Adjuvant (CFA) onto the dura mater ...

    M. Lukács, K. Warfvinge, J. Tajti, F. Fülöp, J. Toldi… in The Journal of Headache and Pain (2017)

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  2. Article

    Open Access

    KYNA analogue SZR72 modifies CFA-induced dural inflammation- regarding expression of pERK1/2 and IL-1β in the rat trigeminal ganglion

    Neurogenic inflammation has for decades been considered an important part of migraine pathophysiology. In the present study, we asked the question if administration of a novel kynurenic acid analogue (SZR72), ...

    M. Lukács, K. Warfvinge, L. S. Kruse, J. Tajti… in The Journal of Headache and Pain (2016)

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  3. Article

    Open Access

    Kynurenic acid modulates experimentally induced inflammation in the trigeminal ganglion

    The trigeminal ganglion (TG) plays a central role in cranial pain. Administration of complete Freund’s adjuvant (CFA) into the temporomandibular joint (TMJ) elicits activation of TG. Kynurenic acid (KYNA) is a...

    A. Csáti, L. Edvinsson, L. Vécsei, J. Toldi, F. Fülöp… in The Journal of Headache and Pain (2015)

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  4. Article

    Open Access

    In vitro and in vivo multidrug resistance reversal activity by a Betti-base derivative of tylosin

    The multidrug resistance (MDR) proteins are present in a majority of human tumours. Their activity is important to understand the chemotherapeutic failure. A search for MDR-reversing compounds was conducted am...

    N Gyémánt, H Engi, Z Schelz, I Szatmári, D Tóth, F Fülöp… in British Journal of Cancer (2010)

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