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  1. Article

    Open Access

    Antisecretory factor in breastmilk is associated with reduced incidence of sepsis in preterm infants

    Antisecretory Factor (AF) is a protein present in breastmilk that regulates inflammatory processes. We aimed to investigate the level of AF in mothers’ own milk (MOM) in relation to sepsis and other neonatal m...

    Anna Gustafsson, Ewa Johansson, Ewa Henckel, Axel Olin in Pediatric Research (2024)

  2. Article

    Open Access

    Bladder/bowel dysfunction in pre-school children following febrile urinary tract infection in infancy

    An association between bladder-bowel dysfunction (BBD) and urinary tract infection (UTI) is well-known. However, a question less explored is whether children with UTI early in life also have increased prevalen...

    Sofia Sjöström, Ulla Sillén, Marc Bachelard, Ewa Johansson in Pediatric Nephrology (2021)

  3. Article

    Open Access

    Elevated intracranial pressure after head trauma can be suppressed by antisecretory factor—a pilot study

    Control of intracranial pressure (ICP) is a key element in neurointensive care for directing treatment decisions in patients with severe traumatic brain injury (TBI). The anti-inflammatory protein antisecretor...

    Kliment Gatzinsky, Ewa Johansson, Eva Jennische, Merna Oshalim in Acta Neurochirurgica (2020)

  4. Article

    Open Access

    Increased level of compleasomes in cerebrospinal fluid of patients with herpes simplex encephalitis

    Herpes simplex encephalitis (HSE) is a common cause of viral encephalitis (HSV-1) characterised by pronounced inflammation and elevated intracranial pressure. We have shown in a rat model that HSV-1 infection ...

    Ewa Johansson, Stefan Lange, Tomas Bergström, Merna Oshalim in Journal of NeuroVirology (2018)

  5. Article

    Open Access

    Reaction of complement factors and proteasomes in experimental encephalitis

    Herpes simplex virus type 1 (HSV-1) encephalitis causes a deleterious inflammation and elevated intracranial pressure. As a step towards examining the origin of the inflammation, we here report the response of...

    Stefan Lange, Tomas Bergström, Ewa Johansson, Merna Oshalim in Journal of NeuroVirology (2017)

  6. No Access

    Article

    Recombinant or Plasma-Derived Antisecretory Factor Inhibits Cholera Toxin-Induced Increase in Evans Blue Permeation of Rat Intestinal Capillaries

    The effect of cholera toxin on small intestinalcapillary function, utilizing the Evans blue dye method,was analyzed. The modulatory influence of plasma-derivedor recombinant human antisecretory factor on this ...

    Stefan Lange, Dick S. Delbro, Eva Jennische in Digestive Diseases and Sciences (1998)