5 Result(s)
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Etsuko Yamamoto Hattori
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Article
Open AccessDevelopment of extended pharmacokinetic models for propofol based on measured blood and brain concentrations
Propofol’s pharmacokinetics have been extensively studied using human blood samples and applied to target-controlled infusion systems; however, information on its concentration in the brain remains scarce. The...
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Article
Irreversible postoperative cognitive impairment after unruptured intracranial aneurysm treatment in the elderly
Postoperative cognitive dysfunction and recovery remain unclear in older patients undergoing interventional therapies for unruptured intracranial aneurysms (UIAs). This study aimed to compare changes in postop...
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Article
Open AccessSeizure control by adding on other anti-seizure medication on seizure during levetiracetam administration in patients with glioma-related epilepsy
Epilepsy is a major symptom in patients with glioma. Levetiracetam (LEV) is recognized as a first-line treatment for glioma-related epilepsy. Increasing the LEV dose is allowed into patients with seizure occur...
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Article
Open AccessAuthor Correction: A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
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Article
Open AccessA RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
Glioblastoma is the most common adult brain tumour, representing a high degree of malignancy. Transcription factors such as RUNX1 are believed to be involved in the malignancy of glioblastoma. RUNX1 functions ...
