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Article
Utilization of hypofractionated radiotherapy in treatment of glioblastoma multiforme in elderly patients not receiving adjuvant chemoradiotherapy: A National Cancer Database Analysis
To assess the utilization and outcomes of adjuvant monotherapy with hypofractionated radiation (RT) among elderly patients not receiving traditional adjuvant chemoradiotherapy (cRT) for glioblastoma multiforme...
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Article
Radiation emergencies: radiation-related brain and lung injury
The advent of modern radiation techniques, such as intensity modulated and stereotactic ablative radiation therapy, has permitted increasingly accurate delivery of radiation, with ability to shape distribution...
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Article
Evidence of high mortality in long term survivors of childhood medulloblastoma
The diagnosis of pediatric medulloblastoma now carries a much improved overall survival; however as outcomes advance, late mortality, from causes such as disease recurrence and subsequent malignancies, are of...
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Article
Risk of subsequent malignancies in survivors of childhood leukemia
The diagnosis of childhood leukemia now carries a much improved overall survival. With this knowledge comes concern for late effects of therapy, especially the risk of secondary malignancy.
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Article
Late causes of death in children treated for CNS malignancies
As the outcome for pediatric central nervous system (CNS) malignancies improves, data regarding long term effects and risk of early mortality are needed. Using the Surveillance, Epidemiology, and End Results d...
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Article
Patterns of care and outcomes of patients with pleomorphic xanthoastrocytoma: a SEER analysis
To study the clinical characteristics, treatment approach and outcome of pleomorphic xanthoastrocytoma (PXA), patients were identified using the National Cancer Intitute's Surveillance, Epidemiology, and End R...
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Article
Open AccessEsophageal cancer in a young woman with bulimia nervosa: a case report
Adenocarcinoma of the esophagus has increased dramatically within the United States and continues to have a poor prognosis despite aggressive treatment. Identifying potential risk factors is critical for the e...
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Article
Active integration: new strategies for transgenesis
This paper presents novel methods for producing transgenic animals, with a further emphasis on how these techniques may someday be applied in gene therapy. There are several passive methods for transgenesis, s...
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Article
Enhanced radiation damage of tumor vasculature by mTOR inhibitors
It is known that radiation activates the phosphoinositol-3 kinase (PI3K)/Akt pathway and that inhibition of PI3K or Akt sensitizes tumor vasculature to radiotherapy. Mammalian target of rapamycin (mTOR) is a d...
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Article
The use of antisense oligonucleotides in evaluating survivin as a therapeutic target for radiation sensitization in lung cancer
Elucidating the mechanism of over and under expression of proteins is critical in develo** a better understanding of cancer. Multiple techniques are used to examine differential expression of proteins in cel...
