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Article
Open AccessLive sequence charts to model medical information
Medical records accumulate data concerning patient health and the natural history of disease progression. However, methods to mine information systematically in a form other than an electronic health record ar...
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Article
Open AccessReplication of an empirical approach to delineate the heterogeneity of chronic unexplained fatigue
Chronic fatigue syndrome (CFS) is defined by self-reported symptoms. There are no diagnostic signs or laboratory markers, and the pathophysiology remains inchoate. In part, difficulties identifying and replica...
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Article
Open AccessInclusion of the glucocorticoid receptor in a hypothalamic pituitary adrenal axis model reveals bistability
The body's primary stress management system is the hypothalamic pituitary adrenal (HPA) axis. The HPA axis responds to physical and mental challenge to maintain homeostasis in part by controlling the body's co...