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Article
Open AccessPhage display screening of therapeutic peptide for cancer targeting and therapy
Recently, phage display technology has been announced as the recipient of Nobel Prize in Chemistry 2018. Phage display technique allows high affinity target-binding peptides to be selected from a complex mixtu...
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Article
Open AccessSynthetic lethality between HER2 and transaldolase in intrinsically resistant HER2-positive breast cancers
Intrinsic resistance to anti-HER2 therapy in breast cancer remains an obstacle in the clinic, limiting its efficacy. However, the biological basis for intrinsic resistance is poorly understood. Here we perform...
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Article
Open AccessRBM24 suppresses cancer progression by upregulating miR-25 to target MALAT1 in nasopharyngeal carcinoma
Abnormal interaction between non-coding RNAs has been demonstrated to be a common molecular event in various human cancers, but its significance and underlying mechanisms have not been well documented. RNA-bin...
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Article
Selective enrichment of hepatocytes from mouse embryonic stem cells with a culture system containing cholestatic serum
There is increasing evidence indicating that embryonic stem (ES) cells are capable of differentiating into hepatocyte-like cells in vitro. However, it is necessary to improve the differentiation efficiency so as ...