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Article
Open AccessDevelopment of a core outcome set for therapeutic clinical trials enrolling dogs with atopic dermatitis (COSCAD’18)
For decades, the efficacy of interventions in clinical trials enrolling dogs with atopic dermatitis (AD) relied on heterogeneous evaluations of skin lesions and pruritus using unvalidated tools. Although some ...
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Article
Open AccessConcurrent short-term use of prednisolone with cyclosporine A accelerates pruritus reduction and improvement in clinical scoring in dogs with atopic dermatitis
A randomized, unmasked, multicenter study was conducted to evaluate the rate of pruritus reduction and improvement in clinical scoring by cyclosporine A (5 mg/kg orally, once daily for 28 days) either alone (n...
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Article
PNPLA1 mutations cause autosomal recessive congenital ichthyosis in golden retriever dogs and humans
Catherine André, Judith Fischer and colleagues report that mutations in PNPLA1 cause congenital ichthyosis in humans and golden retriever dogs. Their findings suggest a role for PNPLA1 in the formation of the epi...
