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Open AccessPaving the way for more precise diagnosis of EcPV2-associated equine penile lesions
There is growing evidence that equine papillomavirus type 2 (EcPV2) infection is causally associated with the development of equine genital squamous cell carcinomas (SCCs). Early stages of disease present clin...
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Article
Open AccessDevelopment of a core outcome set for therapeutic clinical trials enrolling dogs with atopic dermatitis (COSCAD’18)
For decades, the efficacy of interventions in clinical trials enrolling dogs with atopic dermatitis (AD) relied on heterogeneous evaluations of skin lesions and pruritus using unvalidated tools. Although some ...
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Article
Open AccessItch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors
Chronic itch is a highly debilitating condition affecting about 10% of the general population. The relay of itch signals is under tight control by inhibitory circuits of the spinal dorsal horn, which may offer...
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Article
Open AccessGlucocorticosteroids and ciclosporin do not significantly impact canine cutaneous microbiota
As prednisone and ciclosporin can have immunosuppressive effects and have been considered potential predisposing factors for skin infections, we investigated the impact of these drugs on the diversity of the c...
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Article
Open AccessGeno- and seroprevalence of Felis domesticus Papillomavirus type 2 (FdPV2) in dermatologically healthy cats
Papillomaviruses can cause proliferative skin lesions ranging from benign hyperplasia to squamous cell carcinoma (SCC). However, asymptomatic infection is also possible. Several groups have detected Felis domesti...
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Article
Open AccessTreatment of canine atopic dermatitis: 2015 updated guidelines from the International Committee on Allergic Diseases of Animals (ICADA)
In 2010, the International Task Force on Canine Atopic Dermatitis (now International Committee on Allergic Diseases of Animals, ICADA) published the first consensus guidelines for the treatment of atopic derma...
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Article
Open AccessCanine atopic dermatitis: detailed guidelines for diagnosis and allergen identification
Canine atopic dermatitis (AD) is a common, genetically predisposed, inflammatory and pruritic skin disease. The variation in clinical presentations, due to genetic factors, extent of the lesions, stage of the ...
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Article
Open AccessNovel snake papillomavirus does not cluster with other non-mammalian papillomaviruses
Papillomaviruses (PVs) are associated with the development of neoplasias and have been found in several different species, most of them in humans and other mammals. We identified, cloned and sequenced PV DNA f...