23 Result(s)
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Article
Supplementation with antioxidant micronutrients in pregnant women with obesity: a randomized controlled trial
Obesity increases maternal morbidity and adversely affects child health. Maternal inflammation may play a role in adverse outcomes. The objective of this study was to determine whether providing a higher dose ...
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Article
Perinatal inflammation, fetal growth restriction, and long-term neurodevelopmental impairment in Bangladesh
There are limited data on the impact of perinatal inflammation on child neurodevelopment in low-middle income countries and among growth-restricted infants.
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Life satisfaction for adolescents with developmental and behavioral disabilities during the COVID-19 pandemic
This study aimed to identify contextual factors associated with life satisfaction during the COVID-19 pandemic for adolescents with mental, emotional, behavioral, and developmental (MEBD) disabilities.
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Article
Predictors of urinary biomarker concentrations of phthalates and some of their replacements in children in the Project Viva cohort
Some phthalates are still widely used in food packaging, toys, and personal care products, and links to adverse health have motivated substitution with replacement chemicals. Few studies have examined patterns...
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SPR perspectives: Environmental influences on Child Health Outcomes (ECHO) Program: overcoming challenges to generate engaged, multidisciplinary science
The US National Institutes of Health-funded Environmental influences on Child Health Outcomes (ECHO) Program brings together 69 cohorts and over 57,000 children from across the nation to address five key pedia...
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Open AccessMeta-analysis of epigenome-wide associations between DNA methylation at birth and childhood cognitive skills
Cognitive skills are a strong predictor of a wide range of later life outcomes. Genetic and epigenetic associations across the genome explain some of the variation in general cognitive abilities in the general...
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Article
Open AccessCesarean delivery and metabolic health and inflammation biomarkers during mid-childhood and early adolescence
We assessed differences in plasma levels of metabolic health and inflammation biomarkers during mid-childhood and early adolescence between children born by cesarean section vs. vaginal delivery.
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Associations of maternal non-nutritive sweetener intake during pregnancy with offspring body mass index and body fat from birth to adolescence
The evidence that maternal non-nutritive sweetener (NNS) intake during pregnancy increases childhood obesity risk is conflicting. A potential reason for this is that all prior studies examined childhood body m...
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Mode of delivery, type of labor, and measures of adiposity from childhood to teenage: Project Viva
Cesarean delivery has been linked with childhood obesity. Few studies have examined if this association is attenuated if there is labor prior to delivery. The objective of this current analysis was to examine ...
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Open AccessDNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies
DNA methylation has been shown to be associated with adiposity in adulthood. However, whether similar DNA methylation patterns are associated with childhood and adolescent body mass index (BMI) is largely unkn...
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Open AccessEpigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age
Preterm birth and shorter duration of pregnancy are associated with increased morbidity in neonatal and later life. As the epigenome is known to have an important role during fetal development, we investigated...
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Understanding childhood obesity in the US: the NIH environmental influences on child health outcomes (ECHO) program
Few resources exist for prospective, longitudinal analysis of the relationships between early life environment and later obesity in large diverse samples of children in the United States (US). In 2016, the Nat...
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Maternal obesity and associated offspring diabetes mellitus
A large registry-based study found that maternal overweight and obesity are associated with incident type 2 diabetes mellitus in offspring. The results align with those of prospective cohort studies and emphas...
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Associations of prenatal exposure to impaired glucose tolerance with eating in the absence of hunger in early adolescence
Exposure to impaired gestational glucose tolerance has been shown to have sex-specific associations with offspring obesity risk, perhaps by affecting the development of appetite regulation. We examined the ext...
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Article
Maternal corticotropin-releasing hormone is associated with LEP DNA methylation at birth and in childhood: an epigenome-wide study in Project Viva
Corticotropin-releasing hormone (CRH) plays a central role in regulating the secretion of cortisol which controls a wide range of biological processes. Fetuses overexposed to cortisol have increased risks of d...
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Correction: Maternal obesity and offspring cognition: the role of inflammation
Following publication of this article, the authors noted that the name of the last author was incorrectly displayed as ‘Sen Sarbattama’. This authors name has now been corrected to ‘Sarbattama Sen’. This has b...
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Article
Maternal obesity and offspring cognition: the role of inflammation
High pre-pregnancy body mass index (ppBMI) has been linked to neurodevelopmental impairments in childhood. However, very few studies have investigated mechanisms in human cohorts.
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Article
Open AccessGestational weight gain charts for different body mass index groups for women in Europe, North America, and Oceania
Gestational weight gain differs according to pre-pregnancy body mass index and is related to the risks of adverse maternal and child health outcomes. Gestational weight gain charts for women in different pre-p...
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Article
Associations of the dietary approaches to stop hypertension (DASH) diet with pregnancy complications in Project Viva
The Dietary Approaches to Stop Hypertension (DASH) diet has been shown to improve cardiometabolic outcomes in non-pregnant populations. Little is known regarding the impact of this diet on health during pregna...
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Article
Open AccessSocioeconomic differences in childhood BMI trajectories in Belarus
To examine associations of parental socioeconomic position with early-life offspring body mass index (BMI) trajectories in a middle-income country.
