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Article
Open AccessIntrauterine Exposure to Phthalates and Child Growth in the First Year of Life: Results from the BiTwin Cohort
Phthalates are among the endocrine-disrupting compounds with higher widespread in daily life. Our objective was to assess the associations between maternal exposure to phthalates assessed by urinary phthalate ...
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Article
Open AccessMeasuring the clustering effect of the SARS-CoV-2 transmission in a school population: a cross-sectional study in a high incidence region
Since the beginning of the pandemic, there has been a great deal of controversy regarding the role of schools in the spread of SARS-CoV-2 infection, and the relative contribution of students, teachers, and oth...
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Article
Open AccessMigrant and native women’s perceptions of prenatal care communication quality: the role of host-country language proficiency
Despite the potentially significant impact of women-prenatal care provider communication quality (WPCQ) on women’s perinatal health, evidence on the determinants of those perceptions is still lacking, particul...
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Open AccessCord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth
Rapid postnatal growth may result from exposure in utero or early life to adverse conditions and has been associated with diseases later in life and, in particular, with childhood obesity. DNA methylation, interf...
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Open AccessA sco** review on the impact of austerity on healthcare access in the European Union: rethinking austerity for the most vulnerable
There is consensus that the 2008 financial and economic crisis and related austerity measures adversely impacted access to healthcare. In light of the growing debt caused by the COVID-19 crisis, it is uncertai...
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Open AccessHealth-related quality of life of children born very preterm: a multinational European cohort study
This study aims to (1) describe the health-related quality of life (HRQoL) outcomes experienced by children born very preterm (28–31 weeks’ gestation) and extremely preterm (< 28 weeks’ gestation) at five year...
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Article
Are problematic eating behaviors from 4- to 7-year-old explained by genetic, shared factors or individual characteristics? A longitudinal twin study
Studies based on twins are ideal to disentangle the relative contribution of different factors in the development of eating behaviors. This study aims to evaluate if changes in problematic eating behaviors fro...
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Article
Open AccessTime trends in episiotomy and severe perineal tears in Portugal: a nationwide register-based study
Rates of episiotomy and severe perineal tears (SPT) are indicators of the quality of obstetric care. Time-trends in the reported occurrence of episiotomy and SPT can contribute to understand both, changes in c...
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Open AccessEconomic costs at age five associated with very preterm birth: multinational European cohort study
This study aims to estimate the economic costs of care provided to children born very preterm and extremely preterm across 11 European countries, and to understand what perinatal and socioeconomic factors cont...
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Article
Open AccessMachine learning methods to predict attrition in a population-based cohort of very preterm infants
The timely identification of cohort participants at higher risk for attrition is important to earlier interventions and efficient use of research resources. Machine learning may have advantages over the conven...
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Article
Association of dehydroepiandrosterone sulfate, birth size, adiposity and cardiometabolic risk factors in 7-year-old children
Low birth size (BS) and obesity have been associated with higher dehydroepiandrosterone sulfate (DHEAS) levels in childhood, insulin acting as a mediator, despite contradictory findings. To further explore the...
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Article
Association between Land Use Mix and Respiratory Symptoms and Asthma in Children from the Generation XXI Birth Cohort
Land use mix (LUM) in the neighbourhoods has been associated with healthier lifestyles. However, less is known about the association between LUM and health outcomes, namely during childhood. The objective of t...
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Article
Can serum endoglin be used to improve the diagnostic performance in prostate cancer?
New biomarkers may contribute to avoid unnecessary biopsies resulting from the suboptimal performance of prostate-specific antigen (PSA) testing. This study aimed to assess serum endoglin as a prostate cancer ...
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Open AccessStrategies for assessing the impact of loss to follow-up on estimates of neurodevelopmental impairment in a very preterm cohort at 2 years of age
Loss to follow-up is a major challenge for very preterm (VPT) cohorts; attrition is associated with social disadvantage and parents with impaired children may participate less in research. We investigated the ...
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Article
Provision of Preexposure Prophylaxis at the Portuguese National Health Service and Uptake in the Lisbon Cohort of Men Who Have Sex with Men
We aimed to study the uptake of preexposure prophylaxis (PrEP) before and after its implementation in the Portuguese National Health Service (PNHS) among men who have sex with men (MSM). We studied 6164 partic...
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Open AccessEffectiveness of Nutrition and WASH/malaria educational community-based interventions in reducing anemia in children from Angola
We found no published data in Angola regarding the effect of combining nutrition-specific and nutrition-sensitive approaches in the reduction of anemia in preschool children. Thus, we implemented a cluster-ran...
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Article
Parents’ ratings of post-discharge healthcare for their children born very preterm and their suggestions for improvement: a European cohort study
Follow-up of very preterm infants is essential for reducing risks of health and developmental problems and relies on parental engagement. We investigated parents’ perceptions of post-discharge healthcare for t...
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Open AccessImpact of macro-socioeconomic determinants on sustainable perinatal health care in Portugal: a qualitative study on the opinion of healthcare professionals and experts
The WHO identified the importance of macro-socioeconomic determinants and political context as interlinked key factors affecting healthcare quality and health equity. As a response to the recent economic and f...
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Open AccessUnderstanding participation in European cohort studies of preterm children: the views of parents, healthcare professionals and researchers
Retention of participants in cohort studies is a major challenge. A better understanding of all elements involved in participation and attrition phenomena in particular settings is needed to develop effective ...
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Article
Open AccessMerging academy and healthcare in the Public Health training of medical students
Public Health remains central to understand health and its determinants, and Public Health teams are essential for an integrated collaborative medical practice. However, current teaching of public health to me...