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  1. Article

    Open Access

    HYDROchlorothiazide versus placebo to PROTECT polycystic kidney disease patients and improve their quality of life: study protocol and rationale for the HYDRO-PROTECT randomized controlled trial

    Autosomal dominant polycystic kidney disease (ADPKD) leads to progressive renal cyst formation and loss of kidney function in most patients. Vasopressin 2 receptor antagonists (V2RA) like tolvaptan are current...

    Thomas Bais, Esther Meijer, Bart J. Kramers, Priya Vart, Marc Vervloet in Trials (2024)

  2. Article

    Open Access

    Clinicopathologic features of infection-related glomerulonephritis with IgA deposits: a French Nationwide study

    Infection-related glomerulonephritis with IgA deposits (IRGN-IgA) is a rare disease but it is increasingly reported in the literature. Data regarding epidemiology and outcome are lacking, especially in Europe....

    Elodie Miquelestorena-Standley, Charlotte Jaulerry in Diagnostic Pathology (2020)

  3. No Access

    Article

    Multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney: CT and MRI findings and clinical characteristic

    The aim of this study was to clarify the radiologic and clinical characteristics of multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney.

    Kotaro Yoshida, Naoki Takahashi, Bernard F. King, Akira Kawashima in European Radiology (2019)

  4. Article

    Open Access

    Novel long-range regulatory mechanisms controlling PKD2 gene expression

    Cis-regulatory elements control gene expression over large distances through the formation of chromatin loops, which allow contact between enhancers and gene promoters. Alterations in cis-acting regulatory system...

    Stéphanie Moisan, Stéphanie Levon, Emilie Cornec-Le Gall, Yannick Le Meur in BMC Genomics (2018)

  5. No Access

    Article

    ANCA-associated vasculitis — clinical utility of using ANCA specificity to classify patients

  6. Anti-neutrophil cytoplasmic antibodies (ANCAs) specific for leukocyte proteinase 3 and myeloperoxidase — PR3-ANCAs and MPO-ANCAs, respectively — define distinc...

  7. Divi Cornec, Emilie Cornec-Le Gall, Fernando C. Fervenza in Nature Reviews Rheumatology (2016)

  8. No Access

    Article

    Kidney volume—a crystal ball for ADPKD prognosis?

    A new study has addressed a key question in autosomal dominant polycystic kidney disease (ADPKD): can we predict renal outcome at an early disease stage? Indeed, this information is useful for any patient with...

    Emilie Cornec-Le Gall, Yannick Le Meur in Nature Reviews Nephrology (2014)