![Loading...](https://link.springer.com/static/c4a417b97a76cc2980e3c25e2271af3129e08bbe/images/pdf-preview/spacer.gif)
-
Article
Open AccessHYDROchlorothiazide versus placebo to PROTECT polycystic kidney disease patients and improve their quality of life: study protocol and rationale for the HYDRO-PROTECT randomized controlled trial
Autosomal dominant polycystic kidney disease (ADPKD) leads to progressive renal cyst formation and loss of kidney function in most patients. Vasopressin 2 receptor antagonists (V2RA) like tolvaptan are current...
-
Article
Open AccessClinicopathologic features of infection-related glomerulonephritis with IgA deposits: a French Nationwide study
Infection-related glomerulonephritis with IgA deposits (IRGN-IgA) is a rare disease but it is increasingly reported in the literature. Data regarding epidemiology and outcome are lacking, especially in Europe....
-
Article
Multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney: CT and MRI findings and clinical characteristic
The aim of this study was to clarify the radiologic and clinical characteristics of multiple unilateral subcapsular cortical hemorrhagic cystic disease of the kidney.
-
Article
Open AccessNovel long-range regulatory mechanisms controlling PKD2 gene expression
Cis-regulatory elements control gene expression over large distances through the formation of chromatin loops, which allow contact between enhancers and gene promoters. Alterations in cis-acting regulatory system...
-
Article
ANCA-associated vasculitis — clinical utility of using ANCA specificity to classify patients
Anti-neutrophil cytoplasmic antibodies (ANCAs) specific for leukocyte proteinase 3 and myeloperoxidase — PR3-ANCAs and MPO-ANCAs, respectively — define distinc...
-
Article
Kidney volume—a crystal ball for ADPKD prognosis?
A new study has addressed a key question in autosomal dominant polycystic kidney disease (ADPKD): can we predict renal outcome at an early disease stage? Indeed, this information is useful for any patient with...