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Article
Author Correction: Ephrin receptor A2 is an epithelial cell receptor for Epstein–Barr virus entry
In the version of this Letter originally published, the authors reported on the use of 2,5-dimethylpyrrolyl benzoic acid to block Ephrin receptors. In 2011, it was reported that newly synthesized 2,5-dimethylp...
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Article
Ephrin receptor A2 is an epithelial cell receptor for Epstein–Barr virus entry
Epstein–Barr virus (EBV) is causally associated with nasopharyngeal carcinoma, 10% of gastric carcinoma and various B cell lymphomas 1 . EBV infects both B cells and epithelial c...
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Article
Comprehensive profiling of EBV gene expression in nasopharyngeal carcinoma through paired-end transcriptome sequencing
The latent expression pattern of Epstein-Barr Virus (EBV) genes in nasopharyngeal carcinoma (NPC) has been extensively investigated, and the expression of several lytic genes in NPC has been reported. However,...
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Article
Open AccessNeuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells
Epstein–Barr virus (EBV) is implicated as an aetiological factor in B lymphomas and nasopharyngeal carcinoma. The mechanisms of cell-free EBV infection of nasopharyngeal epithelial cells remain elusive. EBV gl...
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Article
Open AccessEpstein–Barr virus latent genes
Latent Epstein–Barr virus (EBV) infection has a substantial role in causing many human disorders. The persistence of these viral genomes in all malignant cells, yet with the expression of limited latent genes,...
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Article
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins
Combining analysis of host proteome and transcriptome perturbations induced by tumour virus proteins with ongoing genome-wide studies of cancer facilitates the prioritization of cancer genes.
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Chapter
Epstein–Barr Virus Latent Infection Nuclear Proteins: Genome Maintenance and Regulation of Lymphocyte Cell Growth and Survival
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Chapter
LMP1 TRAFficking Activates Growth and Survival pathways
Epstein-Barr Virus (EBV) Latent Infection Membrane Protein 1 (LMP1) is expressed in all the EBV related malignancies. LMP1 expression is critical for transformation of human B-cells by EBV. LMP1 expression in ...
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Chapter and Conference Paper
NF-κB Inhibition in EBV-Transformed Lymphoblastoid Cell Lines
Epstein-Barr virus (EBV) transforms B-l/mphocytes into lymphoblastoid cell lines usur** multiple signaling pathways including NF-κB activation. To determine whether NF-κB activity is essential in the growth ...
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Article
Why commonplace encounters turn to fatal attraction
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Article
Molecular basis for Epstein-Barr virus induced pathogenesis and disease
In summary, information obtained from single gene transfer into EBV-negative cell lines is consistent with molecular genetic analysis of in vitro transformation by the whole virus in emphasizing the role for E...
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Chapter
Epstein-Barr Virus Recombinants: Use of Positive Selection Markers to Rescue Mutants in EBV Negative B Lymphoma Cells
Epstein-Barr virus (EBV) genetic analyses have been restricted because the in vitro host range is limited to primate B lymphocytes which are largely non-permissive for EBV replication (1). Further, recovery of...
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Chapter
Cell Growth Transformation by Epstein Barr Virus
Epstein-Barr Virus (EBV) was discovered 25 years ago during a search for an etiologic agent in human Burkitt lymphoma (BL), a remarkably unusual, geographically restricted, tumor. In vitro infection of primary...
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Chapter
Epstein-Barr Virus Transformation of B Lymphocytes: Molecular Pathogenesis
Primary Epstein-Barr Virus (EBV) infection begins in the oropharynx where the virus establishes persistent infection of epithelial cells through continued cycles of infection, virus replication, cell death, vi...
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Chapter
Persistence and Expression of the Epstein-Barr Virus Genome in Latent Infection and Growth Transformation of Lymphocytes
Epstein-Barr Virus (EBV) is believed to be an important etiologic agent of nasopharyngeal cancers (NPC) especially of the anaplastic type since (i) NPC cells invariably harbor EBV (Wolf et al., 1975; Huang et ...
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Article
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