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  1. Article

    Open Access

    Optimization of human papillomavirus-based pseudovirus techniques for efficient gene transfer

    Human papillomavirus (HPV) L1 and L2 capsid proteins self-assemble into virions capable of efficiently packaging either its 8 kilobase genome or non-viral DNA. The ability of HPV capsids to package non-viral D...

    Timra D. Gilson, Ryan T. Gibson, Elliot J. Androphy in Scientific Reports (2020)

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    Chapter

    Papillomavirus Replication

    Papillomaviruses (PVs) are small, double-stranded, circular DNA viruses that infect mammals, birds, and reptiles. An understanding of these virus replicative cycles is largely derived from studies of bovine pa...

    Sara P. Culleton, Elliot J. Androphy… in Human Papillomavirus (HPV)-Associated Orop… (2015)

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    Article

    Opposing effects of bovine papillomavirus type 1 E6 and E7 genes on Fas-mediated apoptosis

    Programmed cell death (PCD), best exemplified by apoptosis, is a genetically programmed process of cellular destruction that is indispensable for normal development and homeostasis of multicellular organisms. ...

    Yun Liu, Zhiguo Liu, Hua Gao, You Zhou, Elliot J Androphy, Jason J Chen in Oncogene (2005)

  4. No Access

    Article

    The bovine papillomavirus type 1 E6 oncoprotein sensitizes cells to tumor necrosis factor alpha-induced apoptosis

    Expression of viral proteins may result in susceptibility of cells to the cytotoxic effect of Tumor Necrosis Factor Alpha (TNF). While murine C127 cells containing the bovine papillomavirus type 1 (BPV-1) geno...

    Lisa Rapp, Yun Liu, Yihui Hong, Elliot J Androphy, Jason J Chen in Oncogene (1999)

  5. No Access

    Article

    SMN oligomerization defect correlates with spinal muscular atrophy severity

    Spinal muscular atrophy (SMA) is a motor-neuron disorder resulting from anterior-horn–cell death. The autosomal recessive form has a carrier frequency of 1 in 50 and is the most common genetic cause of infant ...

    Christian L. Lorson, John Strasswimmer, Jun-Mei Yao, James D. Baleja… in Nature Genetics (1998)

  6. No Access

    Article

    1H, 15N, and 13C NMR resonance assignments for the DNA-binding domain of the BPV-1 E2 protein

    Sudha Veeraraghavan, Cecilia C. Mello, Karen M. Lee… in Journal of Biomolecular NMR (1998)

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    Article

    A novel method for selective isotope labeling of bacterially expressed proteins

    A novel method for isotope labeling in selected amino acids is presented for use with the T7 RNA polymerase system. The protocol is illustrated with the DNA-binding domain from the E2 protein of bovine papillo...

    Karen M. Lee, Elliot J. Androphy, James D. Baleja in Journal of Biomolecular NMR (1995)

  8. No Access

    Article

    Bovine papillomavirus E2 trans-activating gene product binds to specific sites in papillomavirus DNA

    Enhancers are cis-act ing elements that activate transcription in higher eukaryotes independently of their position or orientation relative to the promoter that they activate1. The mechanisms by which enhancers a...

    Elliot J. Androphy, Douglas R. Lowy, John T. Schiller in Nature (1987)